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Related to Isoelectric focusing: isoelectric point


n. pl. fo·cus·es or fo·ci (-sī′, -kī′)
a. The distinctness or clarity of an image rendered by an optical system.
b. The state of maximum distinctness or clarity of such an image: in focus; out of focus.
c. An apparatus used to adjust the focal length of an optical system in order to make an image distinct or clear: a camera with automatic focus.
a. A point at which rays of light or other radiation converge or from which they appear to diverge, as after refraction or reflection in an optical system: the focus of a lens. Also called focal point.
a. A center of interest or activity: "Precisely how diet affects E. coli in livestock is the focus of current research" (Cindy Engel).
b. Close or narrow attention; concentration: "He was forever taken aback by [New York's] pervasive atmosphere of purposefulness—the tight focus of its drivers, the brisk intensity of its pedestrians" (Anne Tyler).
c. A condition in which something can be clearly apprehended or perceived: couldn't get the problem into focus.
4. Medicine The region of a localized bodily infection or disease.
5. Geology The point of origin of an earthquake.
6. Mathematics A fixed point whose relationship with a directrix determines a conic section.
v. fo·cused, fo·cus·ing, fo·cus·es or fo·cussed or fo·cus·sing or fo·cus·ses
1. To cause (light rays, for example) to converge on or toward a central point; concentrate.
a. To render (an object or image) in clear outline or sharp detail by adjustment of one's vision or an optical device; bring into focus.
b. To adjust (a lens, for example) to produce a clear image.
3. To direct toward a particular point or purpose: focused all their attention on finding a solution to the problem.
1. To converge on or toward a central point of focus; be focused.
2. To adjust one's vision or an optical device so as to render a clear, distinct image.
3. To concentrate attention or energy: a campaign that focused on economic issues.

[New Latin, from Latin, hearth (probably in reference to the fact that a lens or parabolic mirror can concentrate sunlight on a single point to start a fire).]

fo′cus·er n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.focusing - the concentration of attention or energy on something; "the focus of activity shifted to molecular biology"; "he had no direction in his life"
engrossment, immersion, absorption, concentration - complete attention; intense mental effort
particularism - a focus on something particular
2.focusing - the act of bringing into focus
intensification - action that makes something stronger or more extreme
refocusing - focusing again
References in periodicals archive ?
Serum and urine protein separation, followed by immunoprecipitation in serum and urine, and isoelectric focusing of serum and CSF proteins, associated with the borrowing of 2 required devices II.
Isoelectric focusing was performed using IEF (isoelectric focusing)-PAGE pH3-10 (TEFCO).
a pioneer in designing and manufacturing the most reliable, high performance, and high throughput CEInfinite whole column imaging detection capillary isoelectric focusing (iCIEF) systems, proprietary cartridges, ampholytes, and pI standards for the life science industry, is pleased to announce Isogen Life Science B.
SGS Life Science Services has installed and validated instrumentation which uses frequency modulation spectroscopy (FMS) for headspace oxygen analysis of biopharmaceutical container closure systems, as well as imaged capillary isoelectric focusing (icIEF) for analysis of charge distribution and heterogeneity in biopharmaceuticals, at its facility in Mississauga, Canada.
The mixed samples were loaded into the anode cup of Multiphor II IEF system (GE Healthcare Bio-Sciences, Sweden), and first dimensional isoelectric focusing was executed.
Isoelectric focusing (IEF) was performed on Ettan IPGphor III horizontal electrophoresis unit (GE Healthcare, NJ, USA) at 20[degrees]C.
The isoelectric focusing (IEF) program was set as follows: step 1: 250V (linear) for 30min; step 2: 500V (rapid) for 1h; step 3: 4000V (linear) for 4h; step 4: 4000V (rapid) for 30000Vh; and step 5: 500V (rapid) for 20h (holding step).
The scientists used isoelectric focusing to estimate the inhibitor's isoelectric point: 7.
We describe 8 individuals with an unknown Hb variant for which the isoelectric focusing (IEF), citrate agar gel, and HPLC characteristics were suggestive for, but not definitively diagnostic of, Hb Austin.
The protein fractions that showed significant variations were separated by using the technique of electroblotting and electroelution and run on isoelectric focusing (IEF) in second dimension to determine the isoelectric points.
After passive hydration for 12-14 h at room temperature, isoelectric focusing program was: 250 V 10 min, 500 V 30 min, 1000 V 1 h, 9000V 5h, 50000 VH.
The authors studied cord blood serum proteins by profiling a UCB pool of 12 neonates with different backgrounds using a combination of isoelectric focusing and liquid chromatography coupled with matrix-assisted laser desorption/ionization tandem mass spectrometry and by comparing results with metabolic and disease databases available for adult blood.