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Creutz′feldt-Ja′kob disease`(ˈkrɔɪts fɛltˈyɑ kɔp)
a fatal degenerative disease of the human brain, thought to be caused by an abnormal, infectious form of cellular prion protein.
[1965–70; after German physicians Hans German. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)]
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|Noun||1.||Jakob-Creutzfeldt disease - rare (usually fatal) brain disease (usually in middle age) caused by an unidentified slow virus; characterized by progressive dementia and gradual loss of muscle control|