asparaginase

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Related to L-asparaginase: methotrexate, cyclophosphamide, etoposide, vincristine

as·par·a·gin·ase

 (ə-spăr′ə-jə-nās′, -nāz′)
n.
An enzyme isolated from bacteria that catalyzes the hydrolysis of asparagine and is used in the chemotherapeutic treatment of leukemia.

asparaginase

(əˈspærədʒɪˌneɪz; əˈspærədʒɪˌneɪs)
n
(Pharmacology) an enzyme used in treating leukaemia
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.asparaginase - antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemiaasparaginase - antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia
antineoplastic, antineoplastic drug, cancer drug - any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
References in periodicals archive ?
Further, metastasis was found greatly limited by reducing asparagine synthetase, treatment with the chemotherapy drug L-asparaginase, or dietary restriction.
said: "Interestingly, the drug L-asparaginase is used to treat acute
Other drugs included L-Asparaginase (IV), Ondansetron, Prednisone, Risek, and Loritin.
Tenders are invited for Romiplostim, Nplate, Ruxolitinib, Erwina L-Asparaginase contract and 340B
A variety of organisms, from bacteria to Mammals, were reported to produce L-asparaginase (Peterson & Ciegler 1969; Mahajan, Saran, Saxena, & Srivastava, 2013; Zuo et al, 2015).
In a continuing effort, the purpose of the current study was to investigate the influence of a bacterial signal peptide, L-asparaginase II, on the recombinant hGH protein secretion for the first time.
L-asparaginase and L-glutaminase from Aspergillus fumigatus WL002: Production and some physicochemical properties.
L-Asparaginase producing bacteria were isolated from soil samples under optimum conditions using submerged fermentation.
The bird showed partial response to treatment with chlorambucil, lomustine, prednisone, L-asparaginase, and whole-body radiation, with neither evidence of adverse effects nor clinical signs of disease.
Production of L-asparaginase by submerged fermentation was reported with Bacillus cereus MNTG-7 (Audipudi et al.
Results: There were 65 infectious complications in 50 patients during vincristine, daunorubicin, L-asparaginase and dexamethasone induction therapy, including microbiologically documented infections (n = 12; 18.
Urease, L-glutaminase, L-asparaginase, alkaline phosphomonoesterase, and arylsulfatase activities were determined in the rhizospheric soil according to the protocols described by Tabatabai [16, 17].