On average, patients entered the trial with
LDL cholesterol levels of 255 mg/dL, despite treatment with other lipid-lowering therapies, including maximally-tolerated statins, PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors, ezetimibe, LDL apheresis and lomitapide.
3,2019, 1,283 people over age 19 who submitted meal plans as part of the Nutrition and Health Survey saw their
LDL cholesterol go up 1.08 milligrams per deciliter (mg/dL) for every 100 calories of foods eaten at night compared to during the day.
Chante MD (The Philippine Star) - December 2, 2018 - 12:00am The maxim that lower is better for
LDL cholesterol continues to hold true, event at jaw-droppingly low levels of less than 10mg/DL, in a new analysis of data from the FOURIER trial.
Healthcare professionals often refer to
LDL cholesterol as "bad" because the over accumulation of this fatty substance can interfere with blood circulation and increase a person's risk of heart attack or stroke.
The researchers found that serum 25(OH)D was negatively associated with total cholesterol,
LDL cholesterol, HDL cholesterol, and triglycerides after adjustment for age and sex.
More specifically, above-average visit-to-visit variability in fasting triglycerides,
LDL cholesterol, or HDL cholesterol in atorvastatin-treated patients with known coronary artery disease proved to be a strong and independent predictor of coronary and cardiovascular events in a post hoc analysis of the landmark Treating to New Targets (TNT) trial (N Engl J Med 2005;352: 1425-35).
BARCELONA -- The maxim that lower is better for
LDL cholesterol continues to hold true, even at jaw-droppingly low levels of less than 10 mg/dL, in a new analysis of data from the FOURIER trial.
"We therefore raised the question of whether female sex has an impact on reaching the
LDL cholesterol target of less than 70 mg/dl for secondary prevention in clinical practice," Gitt added.
Sabatine, of Brigham and Women's Hospital at Harvard Medical School in Boston, MA, and colleagues note that the clinical benefits of using statins to lower
LDL cholesterol are widely accepted, largely due to the high-quality evidence of their safety and efficacy in clinical trials.
It's called "The Rule of Six," because every increase in statin dosage equates to a six percent improvement in
LDL cholesterol.
Increased concentrations of nonfasting remnant cholesterol are thought to be atherogenic in the same way as
LDL cholesterol, by transport into and accumulation in the arterial wall (1-3).
