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Any of a family of glycoproteins that are components of the basement membrane and mediate cell proliferation, migration, differentiation, and adhesion.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) biochem a glycoprotein in animal tissue that is important in binding together the molecules which form the extracellular matrix
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Natural scaffold is in-turn classified into protein based biomaterials (collagen, fibrin, silk, gelatin, elastin, keratin, actin and myosin, laminin and vitronectin) and polysaccharide based biomaterials (Agarose, alginate, hyaluronan, chitosan, amylase, dextran, cellulose and glycosaminoglycans).
OFM was shown to retain residual basement membrane components, such as laminin, collagen IV and collagenous microarchitecture comprised of fibronectin, glycosaminoglycans and elastin.
The sections were incubated in appropriate secondary antibodies: Cy3-conjugated AffiniPure goat anti-mouse IgG (Jackson ImmunoResearch, West Grove, USA; 1:1,000) for Pax7 and Alexa Fluor 488 goat anti-rabbit IgG (Molecular Probes, Breda, Netherlands; 1:1,000) for laminin. After incubation, the sections were stained with 4,6-diamidino-2- phenylindole (DAPI) diluted in PBS at RT for 5 min.
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E-cadherin, laminin and collagen IV antibodies were obtained from Abeam (Cambridge, UK), [alpha]-SMA antibody was purchased from DAKO (Produktionsvej 42, DK2600 Glostrup, Denmark).
Naturally derived biopolymers such as derivatives of carbohydrates and collagen, elastin, laminin, and fibronectin are used for drug delivery and skin soft tissue utilization.
Carcinoma cells have the ability to transform fibroblasts into reactive myofibroblasts, which synthesize different ECM components: collagen, fibronectin, tenascin, versican, galectin, laminin and others.
Within the central nervous system, extracellular matrix substances such as collagen and laminin promote the regeneration, differentiation, adhesion and migration of nerve fibers.
ECM consists of several distinct components (Figure 1) which can be divided into three groups: i) structural proteins, such as collagen and elastin, ii) specialized adhesion proteins, such as fibronectin, fibrilin, and laminin, iii) glycosaminoglycans (GAG) and proteoglycans (PG).
Our example will be Laminin synthesis and production, and we are interested in ancillary business-related material.
The capsule is secreted by the cells it surrounds and is composed of laminin, collagen IV, entactin/nidogen, and heparan sulfate proteoglycans including perlecan [1-3].
Price, "Presence of laminin fragments in cyst fluid from patients with autosomal dominant polycystic kidney disease (ADPKD): role in proliferation of tubular epithelial cells," Biochimica et Biophysica Acta: Molecular Cell Research, vol.