Natural scaffold is in-turn classified into protein based biomaterials (collagen, fibrin, silk, gelatin, elastin, keratin, actin and myosin, laminin
and vitronectin) and polysaccharide based biomaterials (Agarose, alginate, hyaluronan, chitosan, amylase, dextran, cellulose and glycosaminoglycans).
OFM was shown to retain residual basement membrane components, such as laminin
, collagen IV and collagenous microarchitecture comprised of fibronectin, glycosaminoglycans and elastin.
The sections were incubated in appropriate secondary antibodies: Cy3-conjugated AffiniPure goat anti-mouse IgG (Jackson ImmunoResearch, West Grove, USA; 1:1,000) for Pax7 and Alexa Fluor 488 goat anti-rabbit IgG (Molecular Probes, Breda, Netherlands; 1:1,000) for laminin
. After incubation, the sections were stained with 4,6-diamidino-2- phenylindole (DAPI) diluted in PBS at RT for 5 min.
Member Companies: Safari Circuits, Oliver-Tolas Healthcare Packaging, Keystone Solutions Group, DornerWorks, Koops, Grand Rapids Foam Technologies, Active Manufacturing, Creative Foam, Humphrey Products, Alticor/Access Business Group International, Amerikam, Amtech Electrocircuits, Autocam Medical, Emerald Medical, Extol, Firstronic, JR Automation Technologies, Kent Manufacturing, Laminin
Medical Products, Marketlab, Medbio, Michigan Spring & Stamping, Motion Dynamics Corporation, Packaging Compliance Labs, Ranir, Rose Medical, SSI Electronics, Grand Rapids SmartZone
and collagen IV antibodies were obtained from Abeam (Cambridge, UK), [alpha]-SMA antibody was purchased from DAKO (Produktionsvej 42, DK2600 Glostrup, Denmark).
Naturally derived biopolymers such as derivatives of carbohydrates and collagen, elastin, laminin
, and fibronectin are used for drug delivery and skin soft tissue utilization.
Carcinoma cells have the ability to transform fibroblasts into reactive myofibroblasts, which synthesize different ECM components: collagen, fibronectin, tenascin, versican, galectin, laminin
Within the central nervous system, extracellular matrix substances such as collagen and laminin
promote the regeneration, differentiation, adhesion and migration of nerve fibers.
ECM consists of several distinct components (Figure 1) which can be divided into three groups: i) structural proteins, such as collagen and elastin, ii) specialized adhesion proteins, such as fibronectin, fibrilin, and laminin
, iii) glycosaminoglycans (GAG) and proteoglycans (PG).
Our example will be Laminin
synthesis and production, and we are interested in ancillary business-related material.
The capsule is secreted by the cells it surrounds and is composed of laminin
, collagen IV, entactin/nidogen, and heparan sulfate proteoglycans including perlecan [1-3].
Price, "Presence of laminin
fragments in cyst fluid from patients with autosomal dominant polycystic kidney disease (ADPKD): role in proliferation of tubular epithelial cells," Biochimica et Biophysica Acta: Molecular Cell Research, vol.