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Any of a family of glycoproteins that are components of the basement membrane and mediate cell proliferation, migration, differentiation, and adhesion.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) biochem a glycoprotein in animal tissue that is important in binding together the molecules which form the extracellular matrix
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References in periodicals archive ?
Approximately 40% of patients with CMD have a primary deficiency (MDC1A) of the laminin alpha-2 chain of merosin (laminin-2) due to autosomal recessive variants in the LAMA2 gene.
leprae specifically bind to alpha-Dystroglycan (alpha-DG) in the presence of the G domain of the alpha2 chain of laminin-2. (20) Using alpha2 laminins as a probe, a major protein in the M.
A 21 kDA surface protein of Mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion.