The first call was for candidate vaccines against Lassa virus
, Middle East Respiratory Syndrome coronavirus (MERS-CoV), and Nipah virus.
Laboratory confirmation was performed by using RT-PCR by means of the RealStar Lassa Virus
RTPCR Kit (Altona Diagnostics, https://www.altona-diagnostics.com), the LF diagnosis protocol developed by Nikisins et al.
Proper storage of our food items prevents rats from feeding on them; especially the transmission of Lassa virus
,' he said.
The Lassa virus
is most commonly transmitted to humans from an infected rodent known as the multimammate rat.
As agricultural land expands, the mouse that carries Lassa virus
is forced out of fields and moves into human homes.
Neighboring countries have also declared the presence of the rodent vector of Lassa virus
and the occurrence of epidemics in this region [5,8-12].
Upon identification of the cluster, oral swab and blood specimens from patients were immediately tested in Liberia for Ebola virus and Lassa virus
; both were ruled out.
The CDC reclassification of the Lassa virus
as a Category A pathogen turned Lassa fever into a threat against United States national security interests, opening up funding incentives and research possibilities for Western scientists and biotech companies.
The findings indicated that a combination of three monoclonal antibodies and gave them to nonhuman primates, beginning up to eight days, following exposure to a lethal amount of Lassa virus
In the virus yield reduction assay with Vero cells on days 3 and 5 post-infection, the 90% effective concentration ([EC.sub.90]) values against Lassa virus
(LASV) were 1.7 and 11.1 [micro]g/mL, respectively.
Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus
, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR.
The relevance of this intriguing mechanism of viral entry is further reinforced by recent work on Lassa virus
, an Old World Arenavirus that, similarly to Ebola virus, causes severe to fatal hemorrhagic disease in humans [48, 136].