Leber disease

(redirected from Leber hereditary optic neuropathy)
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Translations

Leber disease

n. enfermedad de Leber, tipo de atrofia hereditaria que causa degeneración del nervio óptico y que afecta a los hombres.
References in periodicals archive ?
GenSight Biologics' lead product candidate, GS010, is in Phase III trials in Leber Hereditary Optic Neuropathy, a rare mitochondrial disease that leads to irreversible blindness in teens and young adults.
Leber hereditary optic neuropathy (LHON) is the most common inherited optic neuropathy [1] with the prevalence ranging from 1:31000 to 1:50000 [2].
Davis et al., "Gene therapy for Leber hereditary optic neuropathy: initial results," Ophthalmology, vol.
Leber hereditary optic neuropathy (LHON) is a mitochondrial disease that mostly causes blindness in young adult males.
One such disease is Leber hereditary optic neuropathy, which afflicts perhaps 1 in 15,000 people and is characterized by vision loss beginning in patients' teens and 20s.
Additionally, the LHON m.11778G>A Novallele Genotyping Assay detects a SNP of the LHON gene, which may play a role in Leber hereditary optic neuropathy (LHON).
Fan et al., "Mouse mtDNA mutant model of Leber hereditary optic neuropathy," Proceedings of the National Academy of Sciences of the United States of America, vol.
Pedigree analysis in Leber hereditary optic neuropathy families with a pathogenic mtDNA mutation.
(2003) The epidemiology of Leber hereditary optic neuropathy in the North East of England.
Idebenone treatment in patients with Leber hereditary optic neuropathy. Invest Ophthalmol Vis Sci 2009;50(Suppl):S1440.
Washington, Aug 05 ( ANI ): By borrowing a tool from bacteria that infect plants, researchers have developed a new approach that can be used to treat a variety of mitochondrial diseases, including the degenerative eye disease Leber hereditary optic neuropathy (LHON).
Huoponen, "Leber hereditary optic neuropathy: clinical and molecular genetic findings," Neurogenetics, vol.