lentivirus

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len·ti·vi·rus

 (lĕn′tĭ-vī′rəs)
n. pl. len·ti·vi·rus·es
Any of a group of retroviruses of the genus Lentivirus that cause diseases with a long latent period and a slow, progressive course. HIV is a lentivirus.

[New Latin Lentivīrus, genus name : Latin lentus, slow + virus.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

lentivirus

(ˈlɛntɪˌvaɪrəs)
n
(Microbiology) any of a group of slowly acting viruses that includes the human immunodeficiency virus (HIV), which causes AIDS
[C20: from Latin lentus slow + virus]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

len•ti•vi•rus

(ˈlɛn təˌvaɪ rəs)

n., pl. -rus•es.
any slow virus of the genus Lentivirus, of the retrovirus family, causing brain disease in sheep and other animals.
[1980–85; lenti (cular) + virus]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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RP-L102 is Rocket's lentiviral vector -based gene therapy in development for patients with FA with Rocket's collaboration partners at Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT) in Spain, CIBER-Rare Diseases and IIS-Fundacion Jimenez Diaz.
Oxford BioMedica will work with the UK Cystic Fibrosis Gene Therapy Consortium (GTC) and Imperial Innovations to develop a long-term therapy for patients with cystic fibrosis, focusing on a novel, replication deficient lentiviral vector, in an inhaled formulation, to selectively introduce a CFTR gene into the relevant target cell.
The ability to switch on and off the expression of transgenes delivered via lentiviral vectors is desirable in a number of experimental and therapeutic situations in which the transgene product must be regulated in a timely manner.
In the present study, we constructed lentiviral vectors to knock down NLRP3 to evaluate the role of the NLRP3 inflammasome in atherosclerosis in apolipoprotein (Apo) E-deficient mice, which can develop severe hypercholesterolemia and spontaneous atherosclerosis [12].
AMSBIO has announced a new range of ready-to-use lentiviral particles that allow direct visualization of organelles or structures in cells without manipulation.
"The lentiviral gene therapy technique, which was pioneered by Dr.
Led by Darrell Kotton, the scientists introduced gene-carrying lentiviral vectors into the windpipe of mice.
Among their topics are targeted gene silencing in solid tumors with electrically mediated siRNA delivery, silencing virus replication, RNAi in the malaria vector Anopheles gambiae, lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi, studying autoimmunity by in-vitro RNA interference, and alternative splicing as a therapeutic target for human diseases.
United States Patent 6,555,342 B1 provides key intellectual property for the packaging of lentiviral and retroviral gene transfer vectors.
The MPS-I program has shown clinical data in an ongoing proof-of-concept study in patients with the severe Hurler subtype, who were treated with ex vivo autologous HSC gene therapy, referred to as OTL-203, using a cryopreserved formulation and a lentiviral vector.
(NASDAQ: RCKT) has inked a research agreement to support the clinical development of its lentiviral vector -based gene therapy programmes in Leukocyte Adhesion Deficiency-I (LAD-I) and Infantile Malignant Osteopetrosis towards registrational trials, the company said.