launch of Fluvastatin Sodium Extended-release Tablets, 80 mg, which is the generic version of Novartis' Lescol
The statin drugs Lescol
(fluvastatin) Pravachol (pravastatin), and Crestor (rosuvastatin) are unaffected by amiodarone.
Some brand-name statins such as Lescol
and Pravachol saw their prescriptions decline, while generic lovastatin prescriptions increased 15.
One recent launch into this sector has been Wyke Farms' Lescol
, which tastes like Cheddar while being significantly lower in saturated fat.
The lipid-lowering drug fluvastatin reduces the risk of premature cardiovascular death in renal transplant recipients, according to the results of the Assessment of Lescol
in Renal Transplantation (ALERT) trial.
According to the agency, all six statins--the others are Lipitor (atorvastatin), Lescol
(fluvastatin), Mevacor (lovastatin), Pravachol (pravastatin), and Xocor (simvastatin)--carry a slight risk of liver or kidney complications, including rhabdomyolysis (rhabdo), a muscle disorder that can lead to kidney failure.
Zocor (simvastatin), Lipitor (atorvastatin), Lipobay (cerivastatin), Lescol
(fluvastatin), Lipostat (pravastatin)
However, many drugs are expected to lose their patent in the coming years like Lipitor (atorvastatin) and Lescol
(fluvastatin) losing patent by 2011, followed by Niaspan (Niacin) in 2013, Pravachol (pravastatin) in 2014 and Crestor (rosuvastatin) in 2016.
Among both private and Medicare plans, AstraZeneca's Crestor and Pfizer's Lipitor receive substantially higher rates of preferential reimbursement compared with Novartis' Lescol
and Kowa's Livalo due to the abundance of available outcomes data.
The patents of Zetia, Vyotrin, Lescol
, Livalo and Lovaza are set to expire between 2012 and 2014.
Patrick W Serruys and his associates in the Lescol
Intervention Prevention Study.
ATLANTA -- Routinely placing patients on a statin early after their first percutaneous intervention reduced their 4-year incidence of major cardiac events by 22% in the Lescol
Intervention Prevention Study (LIPS).