leukodystrophy

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leukodystrophy

(ˌluːkəʊˈdɪstrəfɪ)
n, pl -phies
(Pathology) pathol any of several progressive disorders characterized by the degeneration of white matter or myelin
References in periodicals archive ?
In the present study, white matter disease was seen in 2 (4.65%) patients who presented with leucodystrophy. They are proven to be associated with epilepsy by Guissard et al and Hsieh et al, but their contribution has not been accounted for by any study.
The neuropathy of Krabbe's infantile cerebral sclero-sis (globoid cell leucodystrophy).
Alexander disease (fibrinoid leucodystrophy), originally described by Alexander in 1949, (1) is a rare, fatal, nonfamilial leucoencephalopathy caused by astrocyte dysfunction characterised by missense mutation in the genes coding for glial fibrillary acidic protein(GFAP).