Leukine


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Leu·kine

 (lo͞o′kīn′)
A trademark for the drug sargramostim.
References in periodicals archive ?
M2 EQUITYBITES-February 5, 2018-Partner Therapeutics receives rights from Sanofi to develop, manufacture and commercialise Leukine
M2 PHARMA-February 5, 2018-Partner Therapeutics receives rights from Sanofi to develop, manufacture and commercialise Leukine
PTx) has acquired the global rights to develop, manufacture, and commercialise immuno-stimulant Leukine (sargramostim) from France-based pharmaceutical firm Sanofi (NYSE: SNY), the company said.
Sanofi Genzyme is developing Leukine for the treatment of acute radiation syndrome, a serious illness that occurs in people exposed to high doses of radiation.
There were detected seasonal variations of Ltryptophan, and the L-tryptophan / amino acids (valine, leukine, isoleukine, tyrosine, phenylalanine) connection, by detecting their significantly lower values in spring compared to other seasons.
IL-2 directly promotes NK function, (83-85) while Leukine induces bone marrow production of macrophages.
Niaz presented data from a study that quoted that 95% of a set of patients showed immune response to leukine (active ingredient: sargramostim), whereas there were some others that elicited far less immunogenicity; for example, Avonex (active gradient: interferon beta-1a); 6%, and Neupogen (active ingredient: filgrastim), zero (0%).
This market is substantial in size and currently includes drugs such as Neupogen, Neulasta, Leukine and Revolade.
Professor John Hamilton who led the research at the University of Melbourne in Australia, said that not only can blocking GM-CSF, which is also known as Leukine, suppress the actual disease, it can also reduce pain in sufferers.
A laboratory-made version of GM-CSF called Leukine has been used for years to boost the immune systems of certain cancer patients.
Lead researcher Professor Huntington Potter said: "Our study, along with the drug's track record for safety, suggests Leukine should be tested in humans as a potential treatment for Alzheimer's disease.
Exciting A laboratory-made version cal led Leukine has been used for years to boost the immune systems of certain cancer patients.