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Related to leuprolide: leuprolide acetate


A drug that is a synthetic polypeptide analog of naturally occurring gonadotropin-releasing hormone, C29H84N16O12, used in its acetate form to treat advanced prostate cancer.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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Leuprolide. A depot form of leuprolide is the most commonly employed agent to pharmacologically lower testosterone to treat a paraphilic disorder.
Depot leuprolide acetate and nafarelin acetate are GnRH analogues approved by the FDA more than 25 years ago for treatment of pelvic pain caused by endometriosis.
Revisions were also made to the protocol for EMBARK, a randomized Phase 3 study of enzalutamide plus leuprolide, enzalutamide monotherapy, and leuprolide alone in men with high-risk non-metastatic HSPC.
In addition, after a discussion of the risks, benefits, and alternatives, he agreed to initiate leuprolide injections (22.5 mg every 3 months).
Elevated testosterone settled after the trial of Leuprolide. Diagnosis of hyperandrogenism was made and bilateral salpingo-oophorectomy was performed.
Miller, "Treatment of leiomyomata uteri with leuprolide acetate depot: a double-blind, placebo-controlled, multicenter study.
To investigate the possible role that estrogens play in gender difference in CASQ1-null mice, we treated for 1 month (3 to 4 months of age) male CASQ1-null mice with Premarin (a mixture of water-soluble-conjugated equine estrogens) and female CASQ1-null mice with leuprolide (a synthetic nonapeptide that functions as a potent gonadotropinreleasing hormone, or GnRH, analogue), to abolish estrogens production.
In that study, 29 premenopausal women, aged 18-45 years, received a single dose of the GnRH agonist leuprolide in order to induce hypoestrogenism and ovarian suppression for the study period.
Synthetic leuprolide acetate and triptorelin acetate are also used safely in the treatment of endometriosis, infertility, and prostate cancer.
The medications most frequently overpaid because of incorrect units of service were adenosine, rituximab, infliximab, leuprolide acetate, and bortezomib.
Approximately 16 months after arrival at the institution, an initial trial of leuprolide acetate (100 pg/kg IM q 14 days X 3 treatments; Lupron Depot, Takeda Pharmaceutical Company Limited, Osaka, Japan), was administered to one turkey to decrease aggression.
Leuprolide acetate (3.75 mg) was injected for three cycles, with an interval of 28 days, to treat leiomyoma.