Leydig cell


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Related to Leydig cell: spermatogenesis, Leydig cell tumor
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Noun1.Leydig cell - a cell in the testes that secretes the hormone testosterone
cell - (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
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Inactive LHCGR variant causes type 1 Leydig cell hypoplasia, which is characterized by the complete absence of male differentiation.
However, further tests revealed she had a rare form of ovarian cancer called Sertoli Leydig Cell. Within five months she developed a 16cm tumour in her abdomen and needed surgery to remove it.
* The administration of BD in mice improved male reproductive parameters such as increasing sex hormone levels (FSH, LH, and testosterone), sperm quality, and Leydig cell number with no effect on the level of androgen receptor gene expression.
The involvement of [Ca.sup.2+] in Leydig cell's testosterone synthesis was suggested by Janszen et al.
Notable abnormalities were the decline of Leydig cell population within the interstitial compartment and the sloughing of germ cells within the seminiferous tubules (Figure 2).
The circumtesticular band of Leydig cell tissue characteristic of other teiid lizards (Lowe & Goldberg 1966) is present in A.
Common androgen secreting ovarian tumors include Leydig cell neoplasm, stromal luteoma, Sertoli-Leydig cell tumor, and ovarian hyperthecosis [5].
Carlier, "Leydig cell origin of testicular carcinoid tumour: immunohistochemical and electron microscopic evidence," Histopathology, vol.
The authors of this study conclude that a hypogonadal state or Leydig cell failure can be induced with zinc deficiency altering testicular steroidogenesis.
To ensure that inherent toxicity of our tested chemicals and their mixtures did not induce a downturn in testosterone synthesis, thereby confounding any genuine anti-androgenic effects, we assessed the functional integrity of the testosterone-producing Leydig cell population by immunolabeling of cytochrome P450 (CYP11A1), a key enzyme of the androgen biosynthesis pathway.
Sertoli-stromal tumors, also known as Leydig cell tumors, are rare, androgen-secreting, virilizing tumors in young women.
Leydig cell transplantation could be a promising alternative to hormone replacement therapy, providing physiological patterns of hormone for a longer period of time.