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 (lī′gənd, lĭg′ənd)
An ion, molecule, or molecular group that binds to another chemical entity to form a larger complex.

[From Latin ligandus, gerundive of ligāre, to bind; see ligate.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈlɪɡənd; ˈlaɪ-)
(Chemistry) chem an atom, molecule, radical, or ion forming a complex with a central atom
[C20: from Latin ligandum, gerund of ligāre to bind]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈlaɪ gənd, ˈlɪg ənd)

1. a molecule, as an antibody, hormone, or drug, that binds to a receptor.
2. a molecule, ion, or atom that is bonded to the central metal atom of a coordination compound.
[1945–50; < Latin ligandus, ger. of ligāre to bind, tie]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.ligand - a substance (an atom or molecule or radical or ion) that forms a complex around a central atom
substance - a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
The ligands and their organotin(IV) complexes were screened for antibacterial, antifungal and antioxidant activities.
Schiff base ligands play important role in the synthesis of Schiff base complexes, since they have ability of forming stable complexes with metal ions (Arquero et al., 1985).
During the past two decades, considerable attention has been paid to the chemistry of the metal complexes with nitrogen and oxygen donor atoms ligands [1-3].
Repligen Corporation announced an agreement with Navigo Proteins for the advancement of exclusive novel affinity ligands used in monoclonal antibody and non-mAb downstream purification processes.
Polymer-metal complexes are an important class of polymers formed by coordination of polymeric ligands with transition metal ions [1].
categorised metal anticancer compounds based on their mode of action, which could be divided into five different classes: [9] (1) the metal has a functional role, (2) the metal has a structural role, (3) the metal is a carrier for main ligands that are delivered in vivo, (4) the metal compound behaves as a catalyst in vivo, and (5) the metal compound is photoactive.
G-protein coupled receptors (GPCRs) play an important role that involves detecting molecules or ligands from the outside of a cell and activating internal signal transduction pathways and cellular responses.
Until recently, this kinetic analysis has rarely been used because of the complexity of kinetic models that describe the possibilities of simultaneous binding and isomerization steps for two ligands. In order to analyze the kinetic behavior of this complex assay system, a kinetic model for a rather general ligand--receptor interaction scheme (Scheme 2) was compiled, taking into consideration different modes of ligand binding and isomerization steps and the simulated influence of ligands A and B on the kinetics of the reporter ligand binding.
The thermodynamic effect of cooperativity may be due to changes in the macromolecule's conformation or redistribution of the electron density at the site due to the influence through oligomers bonds or by the MI between bound ligands via space [17].
In this context, TLR7 ligands are especially promising since they induce robust Th1-biased immune responses [2].