pleural effusion

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Related to Light's criteria: pleural effusion, Meigs syndrome, SAAG

pleural effusion

n.
An exudate of fluid into the pleural cavity.
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8-10] Light's criteria is the gold standard to differentiate transudative pleural effusion from exudative pleural effusion, but it requires four biochemical estimations which in developing countries such as India, may not be feasible in every patient due to economic constraints.
Light's criteria is commonly used in evaluating abnormal PEs.
Objectives: To determine the role of new suggested criteria consisting of lactate dehydrogenase (LDH), total proteins (TP), and adenosine deaminase (ADA) in diagnosis of pleural effusion and differentiate it into transudative and exudative and also to compare it with Light's criteria.
1), (3), (6) This chemical analysis helps to determine whether the fluid is an exudate or a transudate by applying the modified Light's criteria (Table 6).
5) The pleural fluid usually fulfills Light's criteria for a transudative effusion, with the exception of an elevated LDH level.
It has been reported in various studies that Light's criteria have lower specificity, and new recommendations have emerged.
Cut off values of pleural fluid proteins, PF/S protein ratio, pleural fluid LDH, PF/S LDH ratio are fixed according to the Light's Criteria.
Light's criteria revisited: consistency and comparison with new proposed alternative criteria for separating pleural transudates from exudates.
In a comparative analysis of the biochemical parameters used to distinguish between pleural exudates and transudates, the use of Light's criteria was able to classify 94.
Light's criteria (1) is the most commonly used method and it has been found that even Light's criteria misclassifies a large number of effusions (2,3).
Transudative and exudative pleural effusion were distinguished based on protein and LDH levels in pleural fluid and serum as per Light's criteria.