limma


Also found in: Acronyms, Wikipedia.

limma

(ˈlɪmə)
n
any of several musical intervals of small size, such as a semitone
References in periodicals archive ?
limma powers differential expression analyses for RNA-sequencing and microarray studies.
DEGs of AR were identified by the limma package following the process of linear model, contrast model, and DEGs selection.
Smyth, "Limma: linear models for microarray data," Bioinformatics and Computational Biology Solution Using R and Bioconductor, Springer, Berlin, Germany, 2005.
Wu et al., "limma powers differential expression analyses for RNA-sequencing and microarray studies," Nucleic Acids Research, 2015.
For each experimental factor combination item, concentration and post-exposure, a model to estimate the treatment effect was fitted with LIMMA (Smyth, 2004) by including the covariate exposure run as a blocking variable to account for the pairing during an exposure run (exposed vs.
Finally, the limma package in R [13] was used to identify significant DEGs in the POAG ONH and normal ONH samples.
After variance-stabilizing transformation and normalization with the robust spline normalization method in the package lumi of R, differential analysis was performed using package limma for the following groups: (1) 20 [micro]M versus untreated control; (2) 300 [micro]M versus untreated.
The obtained counts were analyzed using the "limma" package (implemented in R environment) specially developed for whole-transcriptome analyses of differentially expressed genes [27].
Differential gene expression of 121 ch-ALL samples carrying the translocation t(9;22)(Philadelphia chromosome positive) and 236 ch-ALL samples without this translocation compared to 72 healthy bone marrow samples was calculated using the limma R-package.
Differentially expressed genes were identified by the linear models for microarray data (Limma) package in R software [7].
To investigate the DEGs associated with CRC, expression files of 50 paired human primary colorectal cancer and corresponding adjacent normal tissues were integrated to screen DEGs using edgeR [24] and limma [25], respectively.