hepatotoxicity

(redirected from Liver toxicity)
Also found in: Medical.
Related to Liver toxicity: toxic hepatitis, Toxic liver disease

hep·a·to·tox·ic·i·ty

 (hĕp′ə-tō-tŏk-sĭs′ĭ-tē, hĭ-păt′ō-)
n.
1. The quality or condition of being toxic or destructive to the liver.
2. The capacity of a substance to have damaging effects on the liver.

hep′a·to·tox′ic (-tŏk′sĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

hepatotoxicity

(ˌhɛpətəʊtɒkˈsɪsɪtɪ)
n
(Medicine) the state or quality of being hepatoxic
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Translations

hep·a·to·tox·ic·i·ty

n. hepatotoxicidad, la tendencia de un fármaco o producto tóxico a dañar el hígado.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
The watchdog in an earlier discussion urged Motif to carry out a further trial to allay concerns over liver toxicity, which emerged following the submission of data from two phase III assessments of the drug.
It is also reported to cause seizures and liver toxicity. Kratom may have a role in treating pain and opioid use disorder, but more research is needed on its safety and efficacy.
And while CBD has been gaining significant recognition in the world of health and wellness, the researchers found that people who use it are at an elevated risk for liver toxicity.
Adaptimmune Therapeutics presented initial safety data from two patients with advanced hepatocellular carcinoma, liver cancer, from the first dose cohort of the ADP-A2AFP study at the annual AACR meeting."We did not observe clinically significant liver toxicity in the two patients treated at a dose of 100 million transduced cells, and these data supported dose escalation to the second cohort.
Several chemotherapeutic agents may cause significant steatosis due to their liver toxicity (4-6).
Toxicities were graded based on the worst episode after treatment, according to the National Cancer Institute Common Terminology Criteria for Adverse Events (version 3.0).[9] Liver toxicity including radiation-induced liver disease (RILD) and CTP score decline was diagnosed after the exclusion of intrahepatic progression and was censored at the time of liver-directed therapies or transplant.
(2018), concerning the use of multi-omics to predict liver toxicity. The in silico side of the project is exemplified by a QSAR publication on blood-brain barrier transport of pesticides (Toporov et al., 2018), and by prediction of LAT-1 transporter substrates, which is also important for drug and toxicant penetration into the brain (Singh and Ecker, 2018).
M2 PHARMA-March 19, 2018-Macrolide Pharmaceuticals' Tool Differentiates Liver Toxicity of Macrolide Antibiotics
EPA will evaluate for liver toxicity, neurotoxicity, and irritation.
The issue is making sure to avoid excessive intake from supplements, which has been associated with vomiting, excessive sweating, low blood pressure, and liver toxicity. Much of the research conducted on choline and reduced risk of Alzheimer's disease, heart disease, and other conditions has been inconclusive.
cambogia, until FDA pressured the manufacturer to withdraw and re-formulate the supplements in 2009, because of liver toxicity concerns.