long-term potentiation


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long-term potentiation

n.
Repeated presynaptic stimulation of a nerve, either naturally or in vitro, that results in the long-lasting increased strength of a synapse and is thought to be necessary for learning and memory formation.
References in periodicals archive ?
Promotion of forskolin-induced long-term potentiation of synaptic transmission by caffeine in area CA1 of the rat hippocampus.
Nitric oxide is required for the induction and heterosynaptic spread of long-term potentiation in rat cerebellar slices.
Effects of antipsychotic D2 antagonists on long-term potentiation in animals and implications for human studies.
Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CAI to the entorhinal cortex.
Two components of long-term potentiation induced by different patterns of afferent activation.
Long-term potentiation (LTP) increases synaptic activity, while long-term depression (LTD) reduces it.
Pregnenolone sulfate enhances long-term potentiation in CA1 in rat hippocampus slices through the modulation of N-methyl-D-aspartate receptors.
Instead, we need to understand the biochemical bases beneath these brain regions: what pharmacological agents, introduced at what time, might increase long-term potentiation (Stella, Schweitzer, & Piomelli, 1997), inhibit synaptic degradation (Pak & Sheng, 2003), and otherwise modulate the synaptic changes that underlie learning and memory (Davis & Squire, 1984)?
Saffron can attenuate the deleterious effect of ethanol on memory registration and retrieval, and prevent ethanol-induced inhibition of hippocampal long-term potentiation Crocin seems to be involved in spatial memory and recognition and blothed scopolamine-induced performance deficits in the step-through passive avoidance and radial water maze tests 'A.
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5.
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy.
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