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Any of various cytokines that are released by activated lymphocytes and regulate many aspects of the immune response.

[lympho- + Greek kīnein, to move; see kinin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pathology) immunol a protein, released by lymphocytes, that affects other cells involved in the immune response
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈlɪm fəˌkaɪn)

any of a group of lymphocyte products that perform various disease-fighting functions, as destroying infected cells.
[1969; lympho (cyte) + -kine < Greek kīneîn to move]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Leukemic cell infiltration to the spongious tissue of the bone, or the paracrine excretion of lymphokines and parathormone-related peptides, or parathormon excreted from leukemic cells or ectopically produced, might all explain the low BMD values at the diagnosis [11].
lymphocytes present in tonsils will also produce gamma interferons and other lymphokines. But the exact role of tonsillar T cells in tumour response is not known.
In other studies, noise exposure has been associated with imbalances of other blood components: magnesium, leukocytes (especially eosinophils and basophiles), blood viscosity, platelet count, lymphokines, triglycerides, sex hormones, and retention of sodium in the kidneys.
Furthermore, levamisole stimulates cytotoxic T cells associated with enhancement of lymphokines production.
T lymphocytes, especially [CD4.sup.+], play important role in wound healing by secreting lymphokines to activate fibroblast, as wound anti-inflammatory agent, and activate factor in major histocompatibility complex (MHC) class II.
In this study, we searched, merged, and selected a list of cytokine-relevant genes which involved chemokines, interferons, interleukins, lymphokines, transforming growth factors, and tumor necrosis factors from Gene database and employed a computational strategy by integrating multiple Cytokine-Chip from genome-wide DNA methylation datasets of SLE, RA, and pSS.
After T-cells sensitization, lymphokines are produced.
Cell mediated response have been characterized by lymphocytes proliferation and lymphokines secretion especially in patients with amoebic liver abscess.
These initial events are followed by production of various inflammatory mediators, which include prostaglandins, leukotrienes, prostacyclins, lymphokines, interferon-[alpha] (IFN-[alpha]), IFN-[gamma], interleukin (IL)-1, IL-8, histamine, 5-hydroxytryptamine, tumor necrosis factor-a (TNF-[alpha]), vasoactive amines, eicosanoids and products of proteolytic cascades (8).
Within these sites, activated T cell subsets (e.g., Th1, Th2, and Th17) contribute to the pathology of RA by secreting T lymphokines and stimulating B cell proliferation and autoantibody production [29].
Previous studies have shown that many, but not all, of the effects of IFN-[gamma] paracrine can be stimulated to [T.sub.H]1 cells to secrete lymphokines [18].
Anderson, "Effects of products of activated leukocytes (lymphokines and monokines) on the growth of malignant trophoblast cells in vitro," American Journal of Obstetrics and Gynecology, vol.

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