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Any of various cytokines that are released by activated lymphocytes and regulate many aspects of the immune response.

[lympho- + Greek kīnein, to move; see kinin.]


(Pathology) immunol a protein, released by lymphocytes, that affects other cells involved in the immune response


(ˈlɪm fəˌkaɪn)

any of a group of lymphocyte products that perform various disease-fighting functions, as destroying infected cells.
[1969; lympho (cyte) + -kine < Greek kīneîn to move]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
interleukin - any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
References in periodicals archive ?
After T-cells sensitization, lymphokines are produced.
Cytokines and lymphokines also influence the phenotypic effect of breast cancer.
The pathway of inflammation involves release of numerous chemical mediators, such as prostaglandins, leukotrienes, prostacyclins, lymphokines and chemokines like interferon-a (IFN-a), interferon a (INF a), interleukin-1 (IL-1), IL-8, histamine, 5-hydroxytryptamine (5-HT), and tissue necrosis factor-a.
Inhibition of the growth of Rickettsia prowazekii in cultured fibroblasts by lymphokines.
Future directions for the treatment of advanced melanoma include identification of predictive biomarkers to guide the choice of therapy, new immune agonist antibodies or checkpoint inhibitors to act in concert with PD-1 inhibitors, adaptive T-cell therapies, and lymphokines, cytokines, vaccines, and targeted therapies that can overcome mechanisms of resistance and work in combination with immunomodulators, Dr.
The c-MYC protein is considered as an important transcriptional regulatory factor during cytogenesis and the gene expression of MYC gene is reported to be associated with several physiological processes that involve hormones, growth factors, cytokines, lymphokines, nutritional status, development, differentiation etc (Levens et al.
The cement is an osteoinductive and cementogenic agent that stimulates immune cells to release lymphokines required for the repair and regeneration of cementum and stimulates bone coupling factors necessary for the bioremineralization and healing of osseous periapical defects.
Descriptions indicate that the macrophages on phagocytosed foreign bodies may cause releases of angiotensin-converting enzymes and lymphokines, which lead to the development of granulomas (7).
The close proximity of lymphoid components and fibroblasts at inflammatory sites and the production of lymphokines which influence fibroblast chemotaxis proliferation and protein synthesis are now well recognised.
The exact mechanism of action of CsA is unknown; however, CsA has the ability to act on the immune system by blocking the biosynthesis of some lymphokines produced by T lymphocytes and interleukine-2 synthesis at the transcriptional level.
8) This immunologic reaction causes the stimulation and differentiation of lymphocytes, which release lymphokines, which in turn activate macrophages for an enhanced bactericidal effect.
The role of lymphokines in wound healing has been studied in a variety of in vitro and in vivo studies.

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