lysosome

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ly·so·some

 (lī′sə-sōm′)
n.
A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion.

ly′so·so′mal adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

lysosome

(ˈlaɪsəˌsəʊm)
n
(Biochemistry) any of numerous small particles, containing digestive enzymes, that are present in the cytoplasm of most cells
ˌlysoˈsomal adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ly•so•some

(ˈlaɪ səˌsoʊm)

n.
a cell organelle containing enzymes that break down proteins and other large molecules into smaller constituents and that disintegrate the cell itself after its death.
[1950–55]
ly`so•so′mal, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

ly·so·some

(lī′sə-sōm′)
A structure in the cytoplasm of many cells that is surrounded by a membrane and contains enzymes that digest food molecules. See more at cell.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lysosome - an organelle found in the cytoplasm of most cells (especially in leukocytes and liver and kidney cells)
cell organ, cell organelle, organelle - a specialized part of a cell; analogous to an organ; "the first organelle to be identified was the nucleus"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
Lysosom
References in periodicals archive ?
The company targets lysosomal enzymes to develop innovative drugs for rare pediatric genetic disorders and selected CNS diseases with high unmet medical needs.
We first tested variants of palmitoyl-4MU containing replacements for the 4MU group that were structurally similar to the leaving groups we used in our previously designed substrates for other lysosomal enzymes (9) (1, see online Data Supplement).
Deficient activity of N-acetylglucosamine-1-phosphotransferase leads to defective posttranslational modification of lysosomal enzymes, promoting the intracellular accumulation of both partly degraded glycosaminoglycans and sphingolipids.
In this study, we showed that all enzyme activities in DBS are closely correlated with the total number of leucocyte, since leucocytes are the main source of lysosomal enzymes. While glycocerebrosidase and galactocerebrosidase presented a positive correlation with the number of neutrophils, sphingomyelinase showed a positive correlation with the number of lymphocytes.
Salivary glands produce the intracellular lysosomal enzymes that hydrolysis the oligosaccharide chains of salivary glycoconjugates.
The activities of lysosomal enzymes ([beta]-glucuronidase, [beta]-N-acetylglucosaminidase, b-galactosidase, cathepsin B, and cathepsin D) were increased significantly in serum and the heart of iso-induced myocardial-infarcted rats (40, 41).
SEEKER quantitatively measures the activity of lysosomal enzymes from newborn dried blood spot specimens.
Remarkably, lysosomal enzymes analyses (cord blood) showed that beta-glucuronidase activity was undetectable; this was further confirmed by subsequent cultured fibroblasts from fetal skin biopsy.
Prince, "Pretreatment with a combination of quercetin and a-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats," Life Sciences, vol.
Decreased expression of lysosomal enzymes in diabetic kidney was recently reported (5), and autophagy was recently proposed as a therapeutic target for diabetic nephropathy (6).
[7.] Tappel A, Zalkin H, Caldwell Ka, Desai ID, Shibko S (1962) Increased lysosomal enzymes in genetic muscular dystrophy.

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