lysosome

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ly·so·some

 (lī′sə-sōm′)
n.
A membrane-bound organelle in the cytoplasm of most cells containing various hydrolytic enzymes that function in intracellular digestion.

ly′so·so′mal adj.

lysosome

(ˈlaɪsəˌsəʊm)
n
(Biochemistry) any of numerous small particles, containing digestive enzymes, that are present in the cytoplasm of most cells
ˌlysoˈsomal adj

ly•so•some

(ˈlaɪ səˌsoʊm)

n.
a cell organelle containing enzymes that break down proteins and other large molecules into smaller constituents and that disintegrate the cell itself after its death.
[1950–55]
ly`so•so′mal, adj.

ly·so·some

(lī′sə-sōm′)
A structure in the cytoplasm of many cells that is surrounded by a membrane and contains enzymes that digest food molecules. See more at cell.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lysosome - an organelle found in the cytoplasm of most cells (especially in leukocytes and liver and kidney cells)
cell organ, cell organelle, organelle - a specialized part of a cell; analogous to an organ; "the first organelle to be identified was the nucleus"
Translations
Lysosom
References in periodicals archive ?
SEEKER quantitatively measures the activity of lysosomal enzymes from newborn dried blood spot specimens.
Substrates (S) and internal standards (IS) for the 6 lysosomal enzymes were manufactured by Genzyme Pharmaceutical and provided by the Newborn Screening Branch of the CDC (8, 13).
Prince, "Pretreatment with a combination of quercetin and a-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats," Life Sciences, vol.
Tappel A, Zalkin H, Caldwell Ka, Desai ID, Shibko S (1962) Increased lysosomal enzymes in genetic muscular dystrophy.
M2 EQUITYBITES-March 31, 2014-biOasis Technologies receives notices of allowance for patent application of Therapeutic Lysosomal Enzymes from Europe and Canada
Both CI-MPR and CD-MPR transport lysosomal enzymes with mannose 6-phosphate bearing N-glycans from the trans-Golgi network to the lysosome, and from the cell surface through the endosome to the lysosome.
3) Other unique anti inflammatory effects of ketoprofen include its anti bradykinin activity, stabilisation of lysosomal enzymes, (4) inhibition of leukotriene release from activated cells and suppression of leukocyte migration.
Other potential mechanisms of the increased serum GLU activity may include impaired glycosylation and trafficking of the enzyme to the organelles, leakage from damaged cells, from the activated Kupffer cells, or due to the decreased clearance of lysosomal enzymes from the blood [1, 8].
Therefore, advanced lipofuscin accumulation may greatly diminish lysosomal degradative capacity by preventing lysosomal enzymes from targeting to functional autophagosomes, further limiting mitochondrial recycling.
Thus multiple enzymes and pathways are affected in this disorder in contrast to mucopolysaccharide diseases (MPSs), wherein individual lysosomal enzymes are defective because of mutated genes.
The research is especially promising because we enhanced the cellular folding and function of mutated lysosomal enzymes, whose deficient function is linked to lysosomal storage diseases, using two distinct categories of FDA-approved drugs that have been shown to be safe and effective for the treatment of high blood pressure and muscle spasms," he added.

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