nitrofurantoin

(redirected from Macrobid)
Also found in: Thesaurus, Medical.
Related to Macrobid: ciprofloxacin, nitrofurantoin

ni·tro·fur·an·to·in

 (nī′trō-fyo͝o-răn′tō-ĭn)
n.
A derivative of nitrofuran, C8H6N4O5, used to treat bacterial infections of the urinary tract.

[nitrofuran + (hydan)toin, one of its constituents; see diphenylhydantoin.]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nitrofurantoin - derivative of nitrofuran used as an antibacterial medicine (trade name Macrodantin) effective against a broad range of Gram-positive and Gram-negative bacterianitrofurantoin - derivative of nitrofuran used as an antibacterial medicine (trade name Macrodantin) effective against a broad range of Gram-positive and Gram-negative bacteria; used to treat infections of the urinary tract
antibacterial, antibacterial drug, bactericide - any drug that destroys bacteria or inhibits their growth
nitrofuran - derivative of furan used to inhibit bacterial growth
References in periodicals archive ?
The most common antibiotics used to treat UTIs are Bactrim and Macrobid, which are usually taken for three to seven days.
Urine cultures grew coagulase-negative Staphylococcus aureus and he was sent home on Macrobid. He then presented shortly thereafter with increasing lethargy and was transferred to our facility where he was found to have an acute kidney injury and pancytopenia of unclear etiology.
Nitrofurantoin (Macrodantin, Macrobid) is frequently used as first-line treatment for uncomplicated urinary tract infections (UTIs) and as prophylaxis for recurrent UTIs.
Nitrofurantoin * Furadantin, Macrodantin, Macrobid, Urotoin
In this randomized trial, 338 women 18 to 45 years old who had acute uncomplicated urinary tract infection (UTI) were randomized to open-label treatment with nitrofurantoin (Macrobid), 100 mg twice daily for 5 days, or trimethoprim-sulfamethoxazole, one double-strength tablet twice daily for 3 days.
The micronized formulation (Macrobid) appears to have the fewest gastrointestinal side effects, so I'd use it as a first choice.
Hooton and his associates recently completed a randomized trial aimed at demonstrating noninferiority (difference of 10% or less) of 5-day nitrofurantoin (Macrobid) 100 mg twice daily, compared with TMP-SMX 160/800 mg twice daily in 303 healthy nonpregnant women aged 18-45 years with uncomplicated acute cystitis.