Evaluation of Small Intestinal Biopsies in Malabsorption Syndromes
Clinical features in CF are similar to common respiratory and gastrointestinal diseases and may mimic with asthma, pneumonia and malabsorption syndromes
Many malabsorption syndromes
, including inflammatory bowel disease, lactose intolerance, and celiac disease, impair the ability of the intestinal tract to absorb calcium," explains Vivian Sobel, MD, an endocrinologist at Weill Cornell Medicine.
The variability in the absorption rates may be explained on the basis of interindividual differences, food, drugs and malabsorption syndromes
Also obese patients and patients with malabsorption syndromes
may need more frequent monitoring.
Drug absorption in gastrointestinal disease with particular reference to malabsorption syndromes
Selection of therapeutic agent should be individualised based on patient-specific factors including fracture history, severity of osteoporosis (T-scores), risk for hip fracture, patterns of BMD, comorbid conditions (such as peptic ulcer disease, gastroesophageal reflux, malabsorption syndromes
, malignancy), cost, and other factors.
In those countries, folate testing could be limited to specific indications such as macrocytic anaemia with peripheral blood morphological changes suggestive of megaloblastosis, alcoholism, malabsorption syndromes
such as coeliac disease (most foods fortified with folic acid are not gluten free), some haemopoietic disorders, and chemotherapy patients.
Monitoring 25(OH) D levels and taking higher doses of vitamin D (such as 2000 IU per day or more) may be worthwhile for selected patients, such as those with advanced age, malabsorption syndromes
, or certain other health conditions, and people with dark skin or minimal sunlight exposure.
The iron absorption test is the simplest way to quantify the stage of iron depletion, and to differentiate dietary deficiency from malabsorption syndromes
Decreased carotene levels are seen in several malabsorption syndromes
, including, but not limited to, some pancreatic diseases, sprue, post-small intestine resection, and celiac disease.
This would include patients with osteoporosis, those with malabsorption syndromes
, patients taking medications interfering with vitamin D, those with chronic kidney disease and older adults.