Marinol and Syndros contain synthetic versions of THC, while Cesamet is a synthetic THC analogue.
The FDA sees potential in these compounds, having approved GW Pharmaceuticals' ((https://www.fool.com/quote/nasdaq/gw-pharmaceuticals/gwph) NASDAQ:GWPH ) Epidiolex, which uses CBD as the active ingredient, as a drug treatment for epilepsy, as well as
Marinol from AbbVie ((https://www.fool.com/quote/nyse/abbvie/abbv) NYSE:ABBV ) and Syndros from Insys Therapeutics ((https://www.fool.com/quote/nasdaq/insys-therapeutics/insy) NASDAQ:INSY ), which contain tetrahydrocannabinol (THC), the psychoactive compound derived from marijuana.
The cannabinoids approved by the Food and Drug Administration include nabilone (Cesamet) and dronabinol (
Marinol), both synthetic cannabinoids indicated for cancer chemotherapy-related nausea and vomiting, along with cannabidiol (Epidiolex), just approved in June 2018 for treatment of some rare pediatric refractory epilepsy syndromes, Dr.
Cannabidiol * Epidiolex Risperidone * Risperdal Dronabinol *
MarinolThis is a much larger dose than the 7mg that is typically ingested by smoking a joint or the 2.5mg in dronabinol (
Marinol).
Dronabinol (
Marinol; AbbVie) is a synthetic drug that is FDA-approved as an appetite stimulant for people with cancer or AIDS.
sativa plant that contains the cannabinoids THC and CBD; Nabilone (Cesamet or Canemes)--oral capsules containing a synthetic cannabinoid similar to THC; Dronabinol (
Marinol or Syndros)--oral capsules or an oral solution containing synthetic delta-9-THC.
The company said the Abbreviated New Drug Application (ANDA) for Dronabinol Capsules USP, 2.5 mg, 5 mg and 10 mg is the therapeutic equivalent to the reference listed drug,
Marinol Capsules 2.5 mg, 5 mg and 10 mg from AbbVie Inc.
A synthetic form of THC, FDA-approved
Marinol, has been on the market for years as an appetite stimulant or antiemetic (to prevent vomiting or nausea).
Marinol (dronabinol) is the prescription-only, FDA-approved product for the treatment of gastrointestinal issues related to AIDS or chemotherapy (Calhoun, Galloway, & Smith, 1998).
The initial dose of
Marinol is 2.5 mg BID and the maximum dose is 20 mg daily.