and Syndros contain synthetic versions of THC, while Cesamet is a synthetic THC analogue.
The FDA sees potential in these compounds, having approved GW Pharmaceuticals' ((https://www.fool.com/quote/nasdaq/gw-pharmaceuticals/gwph) NASDAQ:GWPH ) Epidiolex, which uses CBD as the active ingredient, as a drug treatment for epilepsy, as well as Marinol
from AbbVie ((https://www.fool.com/quote/nyse/abbvie/abbv) NYSE:ABBV ) and Syndros from Insys Therapeutics ((https://www.fool.com/quote/nasdaq/insys-therapeutics/insy) NASDAQ:INSY ), which contain tetrahydrocannabinol (THC), the psychoactive compound derived from marijuana.
The cannabinoids approved by the Food and Drug Administration include nabilone (Cesamet) and dronabinol (Marinol
), both synthetic cannabinoids indicated for cancer chemotherapy-related nausea and vomiting, along with cannabidiol (Epidiolex), just approved in June 2018 for treatment of some rare pediatric refractory epilepsy syndromes, Dr.
Cannabidiol * Epidiolex Risperidone * Risperdal Dronabinol * Marinol
This is a much larger dose than the 7mg that is typically ingested by smoking a joint or the 2.5mg in dronabinol (Marinol
; AbbVie) is a synthetic drug that is FDA-approved as an appetite stimulant for people with cancer or AIDS.
sativa plant that contains the cannabinoids THC and CBD; Nabilone (Cesamet or Canemes)--oral capsules containing a synthetic cannabinoid similar to THC; Dronabinol (Marinol
or Syndros)--oral capsules or an oral solution containing synthetic delta-9-THC.
The company said the Abbreviated New Drug Application (ANDA) for Dronabinol Capsules USP, 2.5 mg, 5 mg and 10 mg is the therapeutic equivalent to the reference listed drug, Marinol
Capsules 2.5 mg, 5 mg and 10 mg from AbbVie Inc.
A synthetic form of THC, FDA-approved Marinol
, has been on the market for years as an appetite stimulant or antiemetic (to prevent vomiting or nausea).
(dronabinol) is the prescription-only, FDA-approved product for the treatment of gastrointestinal issues related to AIDS or chemotherapy (Calhoun, Galloway, & Smith, 1998).
The initial dose of Marinol
is 2.5 mg BID and the maximum dose is 20 mg daily.