For the rizatriptan (Maxalt
, Maxalt-MLT) tablet, animal data suggest low risk.
Recent product introductions from Camber include aripiprazoe (Abilify), lamivudine/zidovudine (Combivir), montelukast (Singulair), pantoprazole (Protonix); raloxifene (Evista), rizatriptan (Maxalt
); sildenafil (Revatio), valsartan (Diovan) and zolmitriptan (Zomig).
In addition, her family physician prescribed Maxalt
(sublingual and oral) for treatment of headaches with a variable clinical response including limited relief or no effect.
This single-dose, crossover, comparative bioavailability study includes 26 healthy volunteers and is intended to evaluate and compare therelative bioavailability and to assess the bioequivalenceof RHB-103 and the reference drug, Maxalt
lingua, marketed in Germany by MSD SHARP & DOHME GMBH.
Placebo pills mislabeled as the migraine drug Maxalt
provided close to as much pain relief as Maxalt
mislabeled as a placebo.
Seven triptans are available, including two that are approved for use in children; rizitriptan (Maxalt
) is approved for children older than age 6 years, and almitriptan (Axert) is approved for those aged 12-17 years.
Each subject received placebo three times and Maxalt
three times, each labeled once as "placebo," once as "Maxalt
," and once as "Maxalt
or placebo." An untreated seventh baseline migraine served as a control condition.
Specific triptans include naratriptan (Amerge), rizatriptan (Maxalt
), sumatriptan (Imitrex), zolmitriptan (Zomig), almotriptan (Axert), frovatriptan (Frova) and eletriptan (Relpax).
Such a move holds the promise of giving consumers access to chronic-condition drugs such as Avapro, Diovan and Atacand for hypertension; Lescol and Tricor for hyperlipidemia; Maxalt
and Zomig for migraine; and Singulair and Xopenex for asthma.
Medications that treat migraines: Anti inflammatories Aspirin (Bayer, Bufferin, Excedrin), ibuprofen (Motrin, Advil), naproxen (Aleve, Nuprin) Triptans Sumatriptan (Imitrex), rizatriptan (Maxalt
), zolmitriptan (Zomig) Ergotamines DHE (dihydroergotamine) nasal spray (Migranal), DHE injection.
The class of triptans include sumatriptan (imitrex), rizatriptan (Maxalt
), zolmitriptan (Zomig), naratriptan (Amerge), almotriptan (Axert), eletriptan (Relpax), and frovatriptan (Frova).