. Trends Endocrinol Metab 1993;4:238-242.
Koutras, "Hyperthyroidism in McCune-Albright syndrome
with a review of thyroid abnormalities sixty years after the first report," Thyroid, vol.
Dehner, "McCune-Albright syndrome
presenting with unilateral macroorchidism and bilateral testicular masses," Pediatric Radiology, vol.
Kottler et al., "Mazabraud syndrome in two patients: clinical overlap with McCune-Albright syndrome
," American Journal of Medical Genetics, vol.
Fibrous dysplasia of bone and McCune-Albright syndrome
. Best Pract Res Clin Rheumatol 2008;22:55-69.
Neonatal McCune-Albright syndrome
with systemic involvement: a case report.
Polyostotic FD in association with cutaneous pigmentation (cafe-aulait spots) and precocious puberty is known as the McCune-Albright syndrome
Clinically FD is divided into three groups (3) (1) monostotic: single bone involvement, which is most common (70%) (2) polyostotic: multiple bone involvement, a less common form (30%), and (3) McCune-Albright syndrome
(MAS), a rare variant of mono/polyostotic disease in which FD is associated with cafe-au-lait macules and/or endocrinopathies (4,5).
This delightful, irreverent book comes to us from Lauren Ruotolo, who has McCune-Albright Syndrome
, a rare genetic disease that caused her to enter puberty at nine months (yes, months, not years), triggered frequent bone fractures, and capped her growth at 4 feet 2 inches, which makes her about as tall as an 8-year-old.
The original description of McCune-Albright syndrome
(MAS) included diffuse fibrous dysplasia, cafe-au-lait macules, and precocious puberty (1,2).
Some of Coby's bones could still crumble because he was diagnosed with neonatal Cushing's McCune-Albright syndrome
. But Michelle, of Salford, Gtr Manchester, said: "He's giving us hope."
* Patients with McCune-Albright syndrome
represent up to 3% of all cases of fibrous dysplasia.