Su, Serum metabonomics
study of the hepatoprotective effect of Corydalis saxicola Bunting on carbon tetrachloride-induced acute hepatotoxicity in rats by (1)H NMR analysis, J.
(2014) Selection and dynamic metabolic response of rat biomarkers by metabonomics
and multivariate statistical analysis combined with GC-MS.
Over the past 20 years, since the first term of the metabolome has been defined, different terms associated with metabolite quantification and quality measurement have been further recommended that include metabolome mapping, metabolic fingerprinting, metabolic profiling, metabolic footprinting, metabolic target analysis to untargeted metabolic profiling, metabonomics
and exometabolomics (3, 8).
reveals plasma metabolic changes and inflammatory marker in polycystic ovary syndrome patients.
Application in 1H NMR metabonomics
. Anal Chem 78(13):4281-4290, PMID: 16808434, https://doi.org/10.1021/ac051632c.
It is necessary to continue the promotion of clinical and basic research on DILI induced by antipsychotic medication in the future, including applied genomics, transcriptomics, proteomics, metabonomics
and other "omics" techniques assessing the incidence of DILI before and after onset and genetics between individuals, as well as studies of immunology, molecular biology, the change of biochemistry and such events, conducting big data analysis, and promoting the study of pathogenesis.
study of the therapeutic mechanism of Gynostemma pentaphyllum and atorvastatin for hyperlipidemia in rats.
: applications and perspectives.
Qiu et al., "Metabonomics
approach to understanding acute and chronic stress in rat models," Journal of Proteome Research, vol.
At present, the use of metabonomics
to analyze the changes of serum metabolites in patients with liver failure by nonbioartificial liver treatment is relatively rare.
Nicholson are considered as pioneers in the metabolomics (metabonomics
) field [18-20].
Fan et al., "Combined application of NMR- and GC-MS-based metabonomics
yields a superior urinary biomarker panel for bipolar disorder," Scientific Reports, vol.