Methide

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Related to Methide: Thiolate

Meth´ide

(Chem.) A binary compound of methyl with some element; as, aluminium methide, Al2(CH3)6.

Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.

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Anisol

References in periodicals archive ?

[14] Nevirapine-induced rash is related to the 12-hydroxylation of nevirapine and is presumed to be due to the conversion of 12-hydroxy metabolite to a reactive quinone methide in skin.

Cutaneous adverse drug reactions from a teaching hospital in Bengaluru: An observational study to determine the spectrum and outcome

This quinone methide is used for treatment of rheumatoid arthritis in traditional Chinese medicine [140].

Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration

Thus curcumin oxidation forms a large number of intermediary metabolites such as quinone methide, peroxyl radical, endoperoxide, spiroepoxide, vinylether, and cyclopentadione [146] leading to the formation of bicyclopentadione [147].

ErbB Proteins as Molecular Target of Dietary Phytochemicals in Malignant Diseases

The reaction likely proceeds through a [C.sub.3]-[C.sub.4] cyclization of a quinone methide intermediate arising from elimination of fluoride anion [24].

Advances in the Preparation of Fluorinated Isoquinolines: A Decade of Progress

da Rocha, Addition of Thiols to o-Quinone Methide: New 2-hydroxy-3- phenylsulfanylmethyl [1,4]naphthoquinones and their Activity Against the Human Malaria Parasite Plasmodium falciparum (3D7), Eur.

Synthesis, Biological, and Computational Study of Naphthoquinone Derivatives Containing Heteroatoms

Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid.

Propofol inhibits invasion and growth of ovarian cancer cells via regulating miR-9/NF-[kappa]B signal

Rietjens, "Structure-activity study on the quinone/quinone methide chemistry of flavonoids,"

Cytoprotective and Cytotoxic Effects of Rice Bran Extracts in Rat H9c2(2-1) Cardiomyocytes

While the mechanism of hepatotoxicity remains poorly characterized, NVP metabolites such as 12OH-NVP and quinone methide have been strongly implicated in the process [17, 18] and evidence for the metabolic activation of NVP through the detection of mercapturates in urine has been previously presented [19].

Proteomic analysis of serum and urine of HIV-monoinfected and HIV/HCV-coinfected patients undergoing long term treatment with nevirapine

Meanwhile, the carbenium ion can also present the reaction of rearrangement due to instability, leading to the formation of different unsaturated bonds (--CH=CH and >C=[CH.sub.2]) by the isomerization of the double bond and hydride and/or methide shifts (Fig.

Electron-beam deposition of polyethylene composite coatings at various initiators and inhibitors

Evidence for the formation of a quinone methide during the oxidation of the insect cuticular sclerotizing precursor 1,2-dehydro-N-acetyldopamine.

The effect of alkylphenols on lobster shell hardening

A wellknown catalysis mechanism includes the formation of a quinone methide intermediate and subsequent Michael type addition with the formation of a methylene group between aromatic rings [3].

Structure and curing mechanism of resol phenol-formaldehyde prepolymer resins/ Resoolsete fenoolformaldehuudvaikude analuus

Two cases of poisoning by mercuric methide. Saint Bartholomew's Hosp Rep 1:141-150.