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Related to Mirapex: Restless Leg Syndrome


A dopamine agonist used in the treatment of Parkinson's disease.

[pr(opyl) + ami(no) + pex-, of unknown meaning + (thiaz)ole.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


n pramipexol m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
At the same time, he noted that "hyper-sexuality" is a "well-established and common impulse control disorder" among Parkinson's patients who take a class of drugs known as dopamine agonists, which include pramipexole (Mirapex) and ropinirole (Requip).
His bradykinesia, rigidity, intention tremor and postural hypotension continued to progress despite escalating doses of Sinemet (Carbidopalevodopa), Mirapex (Pramipexole), and Symmetrel (Amantadine).
These results supported a revision of the Mirapex IR Prescribing Information approved by the FDA in March 2013, which remains in the most recent 2016 version [9].
Dopaminergic Parkinson's disease medications, such as pramipexole (mirapex) and ropinirole (requip), are known to cause orthostatic hypotension (Nolden et al., 2014).
The most common drugs in this category used for sleep, specifically movement disorders, include Sinemet (levodopa/carbidopa), dopamine agonists such as Requip (ropinirole), and Mirapex (pramipexole) both FDA approved for restless legs in recent years.
Pramipexole Dihydrochloride Tablets, the generic version of Mirapex, is available in 0.125-, 0.25-, 0.5-, 0.75-, 1- and 1.5-milligram 90-count bottles.
DAs, such as ropinirole (Requip, Repreve, Ronirol, Adartel) and pramipexole (Mirapex, Mirapexin, Sifrol), are chemicals that act on the postsynaptic terminals within the striatum and activate the postsynaptic receptors to reduce dopamine turnover (Hristova & Roller, 2000).
Pramipexole dihydrochloride tablets, the generic version of Mirapex, is available in 0.125, 0.25, 0.5, 0.75, 1 and 1.5 mg 90-count bottles and is used to treat the signs and symptoms of Parkinson's disease as well as treating restless legs syndrome (RLS).
The company said the PRAMIPEXOLE dihydrochloride extended-release tablets 0.375 mg, 0.75 mg, 1.5 mg, 3 mg and 4.5 mg is the therapeutic equivalent generic version of MIRAPEX ER (pramipexole dihydrochloride) Extended-Release Tablets.
The increased levodopa dosages before the surgeries were as follows: BHL 1# QID, Mirapex 0.5# OID, Requip 1# BID, Stalevo 1# QID.