monoamine oxidase inhibitor

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monoamine oxidase inhibitor

n. Abbr. MAOI
Any of a class of antidepressant drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamine neurotransmitters such as norepinephrine and serotonin.

monoamine oxidase inhibitor

n
(Biochemistry) biochem an agent that inhibits the action of monoamine oxidase. Such inhibitors are used in the treatment of depression. Abbreviation: MAOI

mon′oamine′ ox′idase inhib`itor


n.
any of various substances that block enzymatic breakdown of certain monoamine neurotransmitters and that are used to treat depression. Abbr.: MAOI
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.monoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulatemonoamine oxidase inhibitor - any of a group of antidepressant drugs that inhibit the action of monoamine oxidase in the brain and so allow monoamines to accumulate
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
iproclozide - an antidepressant drug that acts as a monoamine oxidase inhibitor
isocarboxazid, Marplan - a monoamine oxidase inhibitor (trade name Marplan) that is used to treat clinical depression
Nardil, phenelzine - monoamine oxidase inhibitor (trade name Nardil) used to treat clinical depression
tranylcypromine - an antidepressant drug that is a monoamine oxidase inhibitor; administered as a sulfate
References in periodicals archive ?
The research, 'Discovery of Novel Plant Derived Monoamine Oxidase Inhibitors as Potential Neuroprotective Agents' was conducted under the supervision of CPH Associate Professor of Medicinal Chemistry Dr Ashraf Khalil.
Monoamine oxidase inhibitors (MAOIs) have well-established efficacy for treating depression, panic disorder, and social phobia.
By product type, the market is sub-segmented into Selective Serotonin Reuptake Inhibitors (SSRIs), Atypical Antipsychotics, Tricyclic Antidepressants, Tetracyclic Antidepressants (TeCAs), Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs), Benzodiazepines, Monoamine Oxidase Inhibitors, and others.
The global anxiety disorders and depression treatment market segmentation is based on drug class (selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake, atypical antipsychotics, tricyclic antidepressants, tetracyclic antidepressants, monoamine oxidase inhibitors, benzodiazepines, beta-blockers, anticonvulsants).
Monoamine oxidase inhibitors are superior to TCAs in MDD with atypical features such as oversleeping, carbohydrate craving, rejection sensitivity, and mood sensitivity.
Boulton, "On the binding of monoamine oxidase inhibitors to some sites distinct from the MAO active site, and effects thereby elicited," NeuroToxicology, vol.
QuilliChew ER is also contraindicated during treatment with monoamine oxidase inhibitors (MAOIs), and also within 14 days following discontinuation of treatment with an MAOI because of the risk of hypertensive crisis.
Tricyclic antidepressants (TCA), monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenaline reuptake inhibitors (SNRIs) all increase the concentration of monoamine neurotransmitters in the synaptic cleft, with varying degrees of specificity.
Tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs), both older antidepressants, are reserved for patients who have failed treatments with other antidepressants.
Sexual side effects are most often associated with serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSR1s), monoamine oxidase inhibitors (MAOIs) and tricyclic and tetracyclic antidepressants.
Like all of these other drugs, it should not be combined with monoamine oxidase inhibitors (MAOls), such as selegiline (Anipryl, l-deprenyl) and amitraz (Mitaban, also used in Preventic collars).