Finally, antiinflammatory marker IL10 and chemokine monocyte chemotactic protein
1 were found to be upregulated during the course of infection in all the animals, and there were no differences between the 2 groups (Figure 3, panels E, F).
 Nonstandard abbreviations: RANTES, regulated on activation, normal T-cell expressed and secreted; DPP-IV, dipeptidyl peptidase IV; T2D, type 2 diabetes; IGT, impaired glucose tolerance; CDI, 1,1 '-carbonyldiimidazole; CHF, congestive heart failure; hMI, history of myocardial infarction; HBS-P, 0.01 mol/L HEPES, 0.15 mol/L NaCl, and 0.05% vol/vol surfactant P20, pH 7.4; MSIA, mass spectrometric immunoassay; TFA, trifluoroacetic acid; MS, mass spectrometry; HBS-N, 0.01 mol/L HEPES and 0.15 mol/L NaCl; RPA, relative percent abundance; MCP, monocyte chemotactic protein
; PTH, parathyroid hormone; DBP, vitamin D-binding protein.
Previous studies of PlGF showed that it "stimulates vascular smooth muscle cell growth, recruits macrophages into atherosclerotic lesions, upregulates production of tumor necrosis factor--ct and monocyte chemotactic protein
1 by macrophages, and stimulates pathologic angiogenesis," they noted.