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Related to Monosomies: trisomies


Having a chromosome number that is not a multiple of the haploid number for the species.
A cell or an organism characterized by an aneuploid chromosome number.

an′eu·ploi′dy (-ploi′dē) n.
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Noun1.aneuploidy - an abnormality involving a chromosome number that is not an exact multiple of the haploid number (one chromosome set is incomplete)
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies
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References in periodicals archive ?
Cases reclassified as chromophobe RCC had multiple monosomies, with deletions of at least 2 of the chromosomes 1, 2, 6, 10, 13, or 17.
One showed normal 46, XY, but the other patient revealed marker chromosomes of unknown origin, trisomy 12, and monosomies of 8, 13, 14, and 17.
According to this guideline, transfer of euploid embryos should be preferred to mosaic ones and mosaic monosomies to mosaic trisomies.
SD-QF-PCR can act as a standalone test for the detection of DS as well as other ploidy levels including monosomies. Furthermore, the present study, which was conducted in prenatal samples using genomic DNA from patients with DS, reported the sensitivity of this technique as 100%.
These include a 27-year-old pregnant woman with stage IIA Hodgkin lymphoma (9), a 25year-old pregnant woman with deletions of the long arms of chromosomes 9 and 22 in her plasma DNA who was diagnosed with chronic myelogenous leukemia (10), a 37-year-old pregnant woman with monosomies of 13, 18, 21, and X that resulted from stage IV metastatic colon cancer (11), and a 40-year-old pregnant woman with extensive copy number variation who was diagnosed with multiple myeloma (12).
Hoover-Fong et al., "Genomic analysis of partial 21q monosomies with variable phenotypes," European Journal of Human Genetics, vol.