myasthenia gravis

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myasthenia grav·is

 (grăv′ĭs)
n.
A disease characterized by progressive fatigue and generalized weakness of the skeletal muscles, especially those of the face, neck, arms, and legs, caused by impaired transmission of nerve impulses following an autoimmune attack on acetylcholine receptors.

[New Latin : myasthenia + Latin gravis, heavy, severe.]

myasthenia gravis

(ˈɡrɑːvɪs)
n
(Pathology) a chronic progressive disease in which the muscles, esp those of the head and face, become weak and easily fatigued

myasthe′nia gra′vis

(ˈgræv ɪs, ˈgrɑ vɪs)
n.
a disease of impaired transmission of motor nerve impulses, characterized by episodic weakness and fatigability of the muscles, caused by autoimmune destruction of acetylcholine receptors.
[1895–1900; < New Latin: serious muscle weakness]

myasthenia gravis

Weakness in skeletal muscles caused by an abnormality that prevents muscles from contracting.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.myasthenia gravis - a chronic progressive disease characterized by chronic fatigue and muscular weakness (especially in the face and neck); caused by a deficiency of acetylcholine at the neuromuscular junctions
disease of the neuromuscular junction - a disease characterized by impairment of neuromuscular junctions
autoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
Translations

myasthenia gravis

n miastenia grave or gravis
References in periodicals archive ?
"Our inpatient unit receives between 600 to 1,000 patients per year and the most common admissions under neurology service includes acute stroke thrombolysis and intervention, neurological emergencies [including status epilepticus, myasthenic crisis, transverse myelitis, auto immune encephalitis and neuroleptic malignant syndrome]."
We report a case of leptospirosis leading to a myasthenic crisis and subsequent diagnosis of a rare form of myasthenia gravis (MG) in a previously healthy traveler returning to Austria from Southeast Asia.
We then compared the effect of the mediastinal radiation therapy across these different groups using the survival rate, the rate of postoperative myasthenic crisis, and the complete stable remission (CSR) rate as the primary endpoints.
Myasthenic crisis involves a sudden onset of severe muscle weakness that can cause respiratory failure, meaning the patient requires intubation and ventilation, It can be caused by a lack of anticholinesterase medication or precipitating factors such as infection, surgery or stress.
Tracheoesophageal Fistula Caused by Tracheostomy in a Patient with Myasthenia Gravis after a Myasthenic Crisis. Front Neurol 2017;8:217.
[1] Myasthenic crisis (MC) is an uncommon life-threatening neurological emergency.
The clinical presentations of the 1st patient were similar to myasthenic crisis and she, therefore, received plasma exchange.
The seven-year-old female patient presented in this case report had failed initial treatment with anticholinesterase and had undergone monthly intravenous immunoglobulin (IVIG) for nearly one year when she developed myasthenic crisis necessitating mechanical ventilation.
Plasma exchange or intravenous immunoglobulins (IVIg) are used for myasthenic crisis [9].
Indications for plasmapheresis are: bulbar symptoms of disease, myasthenic crisis and optimization of preoperative status of the patient.