myeloblast

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my·e·lo·blast

 (mī′ə-lə-blăst′)
n.
An immature cell of the bone marrow that is the precursor of a myelocyte.

my′e·lo·blas′tic adj.

myeloblast

(ˈmaɪələʊˌblɑːst)
n
(Pathology) a cell that gives rise to a granulocyte, normally occurring in the bone marrow but detected in the blood in certain diseases, esp leukaemia
myeloblastic adj
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.myeloblast - a precursor of leukocytes that normally occurs only in bone marrow
leucocyte, leukocyte, WBC, white blood cell, white blood corpuscle, white cell, white corpuscle - blood cells that engulf and digest bacteria and fungi; an important part of the body's defense system
Translations

my·e·lo·blast

n. mieloblasto, una célula no madura en la serie granulocítica, generalmente presente en la médula ósea.
References in periodicals archive ?
Born with Down syndrome, Ebrahim was diagnosed in June last year with acute myeloid leukaemia (AML), a type of cancer where the bone marrow makes abnormal myeloblasts, a type of white blood cell, red blood cells or platelets.
Blasts look like either lymphoblasts or myeloblasts and present as monomorphic medium-sized cells with irregular nuclei, one or more prominent nucleoli, and scant cytoplasms.
Clinical and laboratory features of seven patients with acute myeloid leukemia (AML)-M2/M3 and elevated myeloblasts and abnormal promyelocytes.
Acute Myeloid Leukemia, the most common acute leukemia (blood and bone marrow cancer) in adults, is characterized by the proliferation of abnormal myeloblasts (a type of white blood cell) in the bone marrow.
A type of cancer in which the bone marrow makes abnormal myeloblasts, red blood cells or platelets, it is a slowly progressing disease that manifests itself in middle-aged people, rarely afflicting children.
BM Aspirate from a patient with Acute Myeloid Leukaemia showing Myeloblasts. Leishman Stain x40
A 71-year-old female with a history significant for hypertension, hepatitis B, and hypothyroidism, underwent bone marrow biopsy which showed a hypercellular bone marrow with >90% cellularity and 81% myeloblasts expressing CD 34 and CD 117 markers, confirming a diagnosis of acute myeloid leukemia (AML).
Tailler et al., "A novel effect of DNA methyltransferase and histone deacetylase inhibitors : NF[kappa]B inhibition in malignant myeloblasts," Cell Cycle, vol.
The bone marrow examination then showed 90% myeloblasts, with immunophenotype CD45dim/117+/13dim/33+/56-/2-/15-/ 14-/11b-/99+/HLA-DR-; CD34 positivity was detected for a subpopulation of 8% of blasts.
Immature myeloid cells or extramedullary proliferation of myeloblasts are present in MS [2].
Undoubtedly, blast crisis, defined as >30% myeloblasts in the circulation [10-12], represents a critical turning point in the CML course triggering a rapid clinicobiological worsening with poor outcomes [10].