Lenalidomide in the myelodysplastic syndrome
with chromosome 5q deletion.
She was taken off the clinical trial and began treatment for a presumed myelodysplastic syndrome
, consistent with the cytogenetics and peripheral blood smear and cell counts.
According to Dr John Pagel, a transplant oncologist and assistant member of the Hutchinson Center's Clinical Research Division, patients over the age of 50 with active, advanced leukemia and myelodysplastic syndrome
pose the most difficult treatment challenges because standard transplant therapy rarely works.
Establishing the incidence of myelodysplastic syndrome
. Br J Haematol 1994; 87 : 743-5.
after acute promyelocytic leukemia: the European APL group experience.
associated with bone marrow fibrosis.
There are about 76,000 new cases of myelodysplastic syndrome
(MDS) each year in the United States, according to the study of the Medicare Standard Analytic File, a random sampling of 5% of patients enrolled in Medicare.
If I understand correctly, it pertains not only to pediatric populations but also to adults, as myelodysplastic syndrome
is usually the disease of older populations.
happens when the production of blood cells by bone marrow is disrupted, usually because the cells being produced are defective and are destroyed before they enter the blood stream.
Extramedullary disease in myelodysplastic syndromes
. Am J Med 1988;85: 589-90.
(2) Patients with SDS are at a high risk for development of bone marrow (BM) failure, myelodysplastic syndrome
, and acute leukemia, and more than 10% of SDS patients develop myelodysplastic syndrome
and/or acute leukemia.
SAN ANTONIO -- The incidence of secondary acute myeloid leukemia and myelodysplastic syndrome
is dramatically increased following dose-intensified regimens of doxorubicin and cyclophosphamide for breast cancer, Dr.