When a cAMP analogue or a PDE3I was administered to cultured cardiac myocytes
transfected with promoter-reporter constructs containing one of the alleles, PDE3A transcription increased with the deletion, or DEL, variant.
In conclusion, author mentions that outcome would need that myocytes
of all sizes must be subdued similarly, so that the frequency distribution holds on to its shape throughout the process.
Immunofluorescence labeling was used to measure the cell surface area, and 3H-leucine incorporation was used to detect the synthesis of total protein in neonatal rat cardiac myocytes
(NRCMs) with the overexpression of miR-24.
Rat's atrial myocytes
showed atrionatriuretic factor (ANF) granules, which were few and disintegrated in most of the granules (Fig.
Attempts to infect athymic mice by intravenous, oral, and intranasal routes were unsuccessful; however, direct injection of spores into the tail and feet led to infection of myocytes
, neural tissue, connective tissue, and bone marrow (10).
The junctional zone has been shown to contain myocytes
with morphologic characteristics differing from those of the typical myocytes
of the outer myometrium.
 demonstrated an increased density of [I.sub.NaL] in cardiac myocytes
isolated from patients with HCM.
Attractive therapeutic strategies include the replacement of affected muscle cells with healthy myocytes
or progenitor cells, thereby restoring skeletal muscle function.
Many studies have revealed that myocytes
and fibroblasts are functionally coupled by gap junctions when fibrosis occurred and may interact and modify impulse conduction via two-way electronic signal [8-10].
Specifically, TGF-[beta]1 induces expression levels of extracellular matrix (ECM) constituents by cardiac fibroblasts (i.e., fibrillar collagen, fibronectin, and proteoglycans), self-amplifies its own expression in both cardiac myocytes
and fibroblast [53, 54], and stimulates the proliferation of fibroblasts and their phenotypic conversion to myofibroblasts [55, 56].
Though the exact mechanism of viral rhabdomyolysis is still unknown, the end result is destruction of myocytes
and the release of toxins into the circulation.
The [I.sub.KAch] current density of left atrial myocytes
in Group H was increased (-100 mV: 14.18 [+ or -] 1.74 pA/pF; +50 mV: 10.75 [+ or -] 1.68 pA/pF), while [I.sub.KAch] current density was 9.92 [+ or -] 1.20 pA/pF (-100 mV), 5.57 [+ or -] 0.59 pA/pF (+50 mV) in Group C, and 11.07 [+ or -] 1.95 pA/pF (-100 mV), 8.25 [+ or -] 0.85 pA/pF (+50 mV) in Group M, respectively (Figure 4(a)-4(d), Figure 5(a), 5(b) and Figure 6(a)-6(c)).