nonoxynol-9

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non·ox·y·nol-9

 (nŏn-ŏk′sə-nôl′nīn′, -nŏl′-, -nōl′-)
n.
A spermicide widely used in contraceptive creams, foams, and lubricants.

[non(ane), alkane having nine carbons (from Latin nōnus, ninth; see noon) + (eth)oxy + (etha)nol + 9 (from from its chain of nine ethoxy groups).]
References in periodicals archive ?
Epithelial disruption is more commonly associated with N-9 spermicide use in high-risk settings, and lesions with epithelial disruption may increase the risk of acquiring HIV.
The finding comes 9 months after the Food and Drug Administration issued a nonbinding draft guidance warning that N-9 could irritate the vagina and rectum and increase STI risk.
In this multicenter, randomized clinical trial comparing the efficacy of N-9 spermicide formulations, participants were randomized to one of five formulations (gel, film, or suppository) for coital use.
The label would also advise consumers that using such contraceptives can increase vaginal irritation, which is thought to be the reason why N-9 may actually increase the possibility of acquiring HIV.
that prompted some local retailers to remove N-9 products from their shelves.
As a result, N-9 should not be used for STI or HIV prevention, according to the report, but couples can rely on condoms to help prevent them.
CDC collected information on types of N-9 contraceptives purchased and family planning program (FPP) guidelines for N-9 contraceptive use.
Condoms lubricated with N-9 should no longer be promoted because there is no evidence that they are more effective in preventing pregnancy or infection than condoms lubricated with silicone.
Centers for Disease Control and Prevention updated its Guidelines for the Treatment of Sexually Transmitted Diseases, also warning against using N-9 for STD prevention.
N-9 is the active ingredient in all over-the-counter contraceptive products and is added in smaller amounts to some sexual lubricants and to the outer surface of some condoms.
Abstract This report summarises the evidence presented to a technical consultation on the safety of N-9 and its effectiveness for protection against pregnancy, sexually transmitted infections and HIV, organized by the World Health Organization Department of Reproductive Health and Research with CONRAD in October 2001.
Further, the results indicate the more frequently they used only N-9 gel (without a condom) to protect themselves, the higher their risk of becoming infected.