Services in Creative BioMart include: Annotate N-linked glycosylation
, Annotate O-linked glycosylation, Annotate C-linked glycosylation, Annotate glycationn, Glycan staining or labeling, Glycoprotein purification or enrichment and Glycoproteome and Glycome Analysis by Mass Spectrometry.
dk/services/NetNGlyc/) for N-linked glycosylation
sites and NetOGlyc 4.
Affects Cell-surface Expression and Ligand Bindung.
These include processing of signal sequences, folding, disulfide bridge formation, and both O- and N-linked glycosylation
For influenza A viruses, modifications of N-linked glycosylation
sites in the globular head of the hemagglutinin protein have been linked to changes in virulence, antigenicity, receptor-binding preference, fusion activity, and immune evasion (4).
EX-CELL Glycosylation Adjust (Gal+) allows users to achieve desired N-linked glycosylation
by increasing the galactose site occupancy on the oligosaccharide to a higher level.
Loss of N-linked glycosylation
from the hemagglutinin-neuraminidase protein alters virulence of Newcastle disease virus.
The technology is said to genetically ligate an external amino acid domain to a therapeutic protein or peptide candidate which results in additional N-linked glycosylation
Integrins, receptors and extracellular matrix (ECM) ligands display altered pattern of N-linked glycosylation
in cells undergoing a malignant transformation (Janik et al.
Mobility shift caused by addition of tunicamyc in-a N-linked glycosylation
inhibitor-to culture indicated the effect of glycosylation on the protein weight and SDS-PAGE protein band pattern.
Because there is no N-linked glycosylation
site in preproBNP, our data indicate that secreted HMW proBNP is O-glycosylated (Fig.