Instead of focusing on the 'dirtiest' gene first, Lynch has found it more effective to address them in the following order: DAO, PEMT, GST, COMT, MAOA, MTHFR, and
NOS3.
Michel, "Isolation and chromosomal localization of the human endothelial nitric oxide synthase (
NOS3) gene," Genomics, vol.
Moreover, we compute the values CN([P.sub.i]) for numerical order scales NOS 1, NOS2, and
NOS3 described in Table 5.
(2009) The -786 T/C polymorphism of the
NOS3 gene is associated with elite performance in power sports.
Single nucleotide polymorphisms (SNPs), ACE rs4341 and
NOS3 rs1799983 have been reported to be associated with coronary artery disease (CAD) and blood pressure (BP)in many but not all studies.
Three genes encode NOS enzymes: NOS1 on chromosome (chr) 12 encodes neuronal NOS (nNOS), NOS2A on chr 17 encodes inducible NOS (iNOS), and
NOS3 on chr 5 encodes endothelial NOS (eNOS).
For nitric oxide synthase 3 (
NOS3), the only non-significant results was observed in the comparison of milk fat production ability using qRT-PCR analysis.
Immunohistochemistry to detect the expression of the NOS1, NOS2, and
NOS3 isoforms (Santa Cruz Biotechnology, Inc., USA; dil.
Three different NOS types are available: neuronal (nNOS or NOS1), inducible (iNOS or NOS2) and endothelial (eNOS or
NOS3).
It was also shown that concomitant presence of
NOS3 T allele and CEPT B1 allele was significantly associated with T2DM (P = 0.004) and CAD (P = 0.002) [83].
In my office, we look at five NOS enzymes, however, it appears as though the
NOS3 D298E is the most significant.
These aspects were labeled as following NOS1 tentativeness, NOS2 empirical basis,
NOS3 subjectivity, NOS4 creativity, NOS5 socio-cultural embeddedness, NOS6 observations and inference, and NOS7 Laws and theories.