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A synthetic opioid antagonist, C20H23NO4, used in its hydrochloride form to treat addiction to alcohol and to opioid drugs such as heroin.

[Blend of naloxone and tre- (probably alteration of tri-, from the three carbon atoms of the propyl group that distinguishes it from naloxone, of which it is a congener).]


(Pharmacology) a narcotic antagonist, similar to morphine, used chiefly in the treatment of heroin addiction
[C20: from N-al(lylnor)ox(ymorph)one, + the arbitrary insertion of -trex-]


(nælˈtrɛk soʊn)

a nonaddictive substance, C20H23NO4, used in the treatment of heroin addiction and opiate overdose.
[1970–75; by rearrangement of parts of its chemical name]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.naltrexone - an oral antagonist against the action of opiates
narcotic antagonist - an antagonist used to counteract the effects of narcotics (especially to counteract the depression of respiration)


n naltrexona
References in periodicals archive ?
According to the company, TROXYCA ER extended-release capsules contain pellets that consist of oxycodone hydrochloride, an opioid agonist, which surround sequestered naltrexone hydrochloride, an opioid antagonist.
It is marketed as its hydrochloride salt, naltrexone hydrochloride, under the trade names Revia and Depade.
The present work aimed to compare the effects of opioid receptors blockade using naltrexone hydrochloride, a potent opioid receptors antagonist with systemic action, during the proliferation period of fetal and neonatal Sertoli cells.
In the addiction treatment arena Mallinckrodt recently has introduced Depade naltrexone hydrochloride USP, used in the treatment of alcohol dependence in conjunction with psychosocial therapies.
An Investigational Agent Comprised Of Oxycodone Hydrochloride And Naltrexone Hydrochloride Extended-Release Capsules, In Subjects With Moderate-To-Severe Chronic Non-cancer Pain
The bulk narcotics business, now over 100 years old, is focused in two areas: natural narcotics, or opiates, used to produce codeine phosphate, morphine sulfate, hydrocodone bitartrate, oxycodone hydrochloride and other ingredients used in a variety of prescription pharmaceuticals, and a line of synthetic-based products, including propoxyphene and meperidine hydrochloride, naltrexone hydrochloride and methylphenidate hydrochloride, made from fine organic chemicals.
EMBEDA contains pellets of an extended-release oral formulation of morphine sulphate, an opioid receptor agonist, with a sequestered core of naltrexone hydrochloride, an opioid receptor antagonist.