"What we've made is a hybrid nanomachine
that uses both designed components and natural biological motors," Kosuri said.
Asanuma, "A DNA nanomachine
powered by light irradiation," ChemBioChem, vol.
Langlois et al., "Trajectories of the ribosome as a Brownian nanomachine
," Proceedings of the National Academy of Sciences of the United States of America, vol.
One such example is a DNA nanomachine
based on an intramolecular i-motif that has been used as a pH sensor inside living cells .
But in the nanomachine
world the things aren't bits packaged in bytes, they're atoms packaged in molecules.
Will we see an injectable nanomachine
system that can mend or clear arterial walls?
Microelectromechanical systems (or MEMS, to be succinct) are one step ahead of their smaller evolutionary cousin, the nanomachine
, in that they are already integral to daily life for many of us.
Among their topics are the biogenesis of cellulose nanofibrils by a biological nanomachine
, poly-electrolyte multilayers for fiber engineering, lignin as a functional biomaterial with potential in surface chemistry and nanoscience, bacterial cellulose and its polymeric nanocomposites, the development and application of naturally renewable scaffold materials for bone tissue engineering, and the template synthesis of nanostructured metals using cellulose nanocrystal.
A major advance in the field occurred in 2007, when David Leigh, a researcher at the University of Edinburgh, revealed that he had built a "nanomachine
" whose parts consisted of single molecules.
To help ensure that the accidental creation of a gray-goo nanomachine
remains a practical impossibility, Drexler's Foresight Institute, a nonprofit organization he founded to "help prepare society for anticipated advanced technologies," has prescribed guidelines for the safe development of NT.
Lanni, "The actin-based nanomachine
at the leading edge of migrating cells," Biophysical Journal, vol.