nedocromil


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Related to nedocromil: cromolyn sodium, nedocromil sodium

ne·doc·ro·mil

 (nə-dŏk′rə-mĭl′)
n.
An anti-inflammatory drug, C19H15N, used in an inhaler in the form of a sodium salt to treat mild-to-moderate asthma.

[ne- (perhaps from 9-ethyl, beginning of the chemical name, referring to the presence of an ethyl group in ninth position) + d(i)- + o(xy)- + shortening and alteration of cromolyn.]
References in periodicals archive ?
There are three drugs in this class that can be used topically in the eye: cromolyn, lodoxamide (Alomide), and nedocromil (Alocril).
Nedocromil sodium exerts its anti-inflammatory and anti-asthmatic effect by inhibiting the activation and activity of multiple inflammatory cells, including mast cells, eosinophils, airway epithelial cells and sensory neurons.
1) Eleven trials that included 899 children and adults compared mast cell stabilizers (sodium cromoglycate, nedocromil, and lodoxamide tromethamine) with placebo.
Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil sodium.
Drugs, such as sodium cromoglycate, nedocromil sodium, pemirolast, and lodoxamide act by stabilizing mast cells.
As with VKC, AKC requires long-term therapy with topical mast cell stabilisers such as sodium cromoglycate, lodoxamide and nedocromil to treat the allergic inflammation in mild cases.
G protein-coupled receptor-35 (GPR35) has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil sodium.
This effect is blocked by nedocromil, suggesting that UGN acts by increasing the activity of chloride channels.
Drugs in this class include olopatadine (Pataday, Patanol), azelastine (Optivar) and nedocromil (Alocril, Lastacaft).
agonist (LABA) needed or leukotriene (LTRA) Alternate Cromolyn or LTRA Medium-dose Treatment or theophylline ICS or nedocromil.