Harness, Adsorption of Water by Anhydrous Nedocromil
Sodium from 20 to 40degC, J.
There are three drugs in this class that can be used topically in the eye: cromolyn, lodoxamide (Alomide), and nedocromil
sodium exerts its anti-inflammatory and anti-asthmatic effect by inhibiting the activation and activity of multiple inflammatory cells, including mast cells, eosinophils, airway epithelial cells and sensory neurons.
1) Eleven trials that included 899 children and adults compared mast cell stabilizers (sodium cromoglycate, nedocromil
, and lodoxamide tromethamine) with placebo.
Ozone-induced mediator release from human bronchial epithelial cells in vitro and the influence of nedocromil
Drugs, such as sodium cromoglycate, nedocromil
sodium, pemirolast, and lodoxamide act by stabilizing mast cells.
Long-term effects of budesonide or nedocromil
in children with asthma.
As with VKC, AKC requires long-term therapy with topical mast cell stabilisers such as sodium cromoglycate, lodoxamide and nedocromil
to treat the allergic inflammation in mild cases.
G protein-coupled receptor-35 (GPR35) has been shown to be a target of the asthma drugs cromolyn disodium and nedocromil
This effect is blocked by nedocromil
, suggesting that UGN acts by increasing the activity of chloride channels.
Drugs in this class include olopatadine (Pataday, Patanol), azelastine (Optivar) and nedocromil
agonist (LABA) needed or leukotriene (LTRA) Alternate Cromolyn or LTRA Medium-dose Treatment or theophylline ICS or nedocromil