pleiotropy

(redirected from Negative pleiotropy)
Also found in: Medical, Encyclopedia.

plei·ot·ro·py

 (plī-ŏt′rə-pē) also plei·ot·ro·pism (-pĭz′əm)
n. Biology
The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated phenotypic effects.

[Greek pleiōn, more; see pelə- in Indo-European roots + -tropism.]

plei′o·tro′pic (plī′ə-trō′pĭk, -trŏp′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

plei•ot•ro•py

(plaɪˈɒ trə pi)

n.
the phenomenon of one gene affecting more than one phenotypic characteristic.
[1935–40]
plei`o•trop′ic (-əˈtrɒp ɪk, -ˈtroʊ pɪk) adj.
plei`o•trop′i•cal•ly, adv.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Alternatively, stabilizing selection may result in relatively high genetic correlations among functionally and developmentally related traits and relatively low correlations among unrelated traits through a balance of positive and negative pleiotropy (Lande 1980, 1984; Cheverud 1984).
The negative pleiotropy detected here was within local mandibular regions.
Morphological integration in the mandible appears to be a feature of the genetic system rather than being due to a balance between positive and negative pleiotropy.