adjuvant

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Related to Neoadjuvant therapy: Integrative Medicine

ad·ju·vant

 (ăj′ə-vənt)
n.
1. A treatment that enhances an existing medical regimen, as a pharmacological agent added to a drug to increase or aid its effect.
2. An immunological agent that increases the antigenic response.
adj.
Contributing to or enhancing an existing medical regimen: adjuvant chemotherapy

[From Latin adiuvāns, adiuvant-, present participle of adiuvāre, to help; see aid.]

adjuvant

(ˈædʒəvənt)
adj
aiding or assisting
n
1. something that aids or assists; auxiliary
2. (Pharmacology) med a drug or other substance that enhances the activity of another
3. (Medicine) immunol a substance that enhances the immune response stimulated by an antigen when injected with the antigen
[C17: from Latin adjuvāns, present participle of adjuvāre, from juvāre to help]
ˈadjuvancy n

ad•ju•vant

(ˈædʒ ə vənt)

adj.
1. serving to help or assist; auxiliary.
2. utilizing drugs, radiation therapy, or other means of supplementary treatment following cancer surgery.
n.
3. a person or thing that aids or assists.
4. anything that aids in removing or preventing a disease, esp. a substance added to a prescription to aid the effect of the main ingredient.
5. a substance admixed with an immunogen in order to elicit a more marked immune response.
[1600–10; < Latin adjuvant-, s. of adjuvāns, present participle of adjuvāre to help; see adjutant]

adjuvant

Medicine. a substance added to a medicinal preparation to assist the action of the principal ingredient.
See also: Drugs
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.adjuvant - an additive that enhances the effectiveness of medical treatment
additive - something added to enhance food or gasoline or paint or medicine
Adj.1.adjuvant - furnishing added support; "an ancillary pump"; "an adjuvant discipline to forms of mysticism"; "The mind and emotions are auxiliary to each other"
supportive - furnishing support or assistance; "a supportive family network"; "his family was supportive of his attempts to be a writer"
2.adjuvant - enhancing the action of a medical treatment; "the adjuvant action of certain bacteria"
materia medica, pharmacological medicine, pharmacology - the science or study of drugs: their preparation and properties and uses and effects
helpful - providing assistance or serving a useful function
Translations
Adjuvans

ad·ju·vant

n. adjutor, agente o sustancia que acentúa la potencia de un medicamento;
___ therapyterapia aditiva o complementaria.

adjuvant

adj adyuvante
References in periodicals archive ?
'There is still a high unmet medical need for the development of treatment methods when pathologic complete response (pCR) is not obtained by neoadjuvant therapy. This application is the first step in providing patients with Kadcyla as a new treatment option of adjuvant therapy,' said Dr.
Multikine (Leukocyte Interleukin, Injection), has received Orphan Drug designation from the FDA for neoadjuvant therapy in patients with squamous cell carcinoma (cancer) of the head and neck.
The patient received 6 Taxol & Carboplatin cycles as neoadjuvant therapy with stationary course of the disease.
To the Editor.--We agree with Khararjian et al (1) that "decreasing unnecessary consultations [would] directly save the health care system money." In our practice, however, we find that intraoperative gross examinations in colorectal resections requested by surgeons are valuable because they ensure that the lesion or lesions of interest are incorporated into the resection specimen, determine the adequacy of the surgical margins, are helpful in evaluating for residual tumor and margins in the specimen after neoadjuvant therapy, allow for proper orientation of the specimen with respect to endoscopic markings (ie, tattoo), identify additional pertinent findings (ie, fistula, perforation, diverticula), and provide important information to the surgeon and the patient's family.
He cites 'neoadjuvant therapy' for locally advanced cancer (metastasized beyond the breast).
By working closely with the FDA and participating in the Real-Time Oncology Review pilot program, we are able to make Kadcyla available for people with residual invasive disease after neoadjuvant therapy much sooner than anticipated," said Sandra Horning, M.D., chief medical officer and head of Global Product Development.
In addition to this, about 15%-27% of patients exhibit complete response to neoadjuvant therapy (4).
In a cohort of 82 high-risk early-stage breast cancer patients receiving neoadjuvant therapy, the change of measurable ctDNA from positive to negative during neoadjuvant treatment predicted therapeutic response, while failure to clear ctDNA after neoadjuvant treatment correlated with poor clinical outcomes.
Nevertheless, the same authors conclude that an increased baseline NLR is a simple, inexpensive and available prognostic marker for OS together with tumor response after neoadjuvant therapy (11).
Nonoperative management of rectal cancer with complete clinical response after neoadjuvant therapy. Ann Surg 2012; 256(6): 965-72.
JUNE 2017 The Scottish Medicines Consortium reject Perjeta for the fourth time - twice each for use for women with HER2 positive metastasized breast cancer, and as a first step to shrink a tumour before surgery, known as neoadjuvant therapy. The drug is available in England and Wales.
The international, multi-centre, two-arm, randomised, open-label and phase III study was designed to assess the efficacy and safety of Kadcyla against Herceptin as an adjuvant therapy in people with HER2-positive eBC who have pathological residual disease in the breast or axillary lymph nodes following neoadjuvant therapy that included Herceptin and taxane-based chemotherapy.