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An abnormal increase in the number of cells in a tissue or organ, with consequent enlargement of the part or organ.

hy′per·plas′tic (-plăs′tĭk) adj.


(Pathology) enlargement of a bodily organ or part resulting from an increase in the total number of cells. Compare hypertrophy
hyperplastic adj


(ˌhaɪ pərˈpleɪ ʒə, -ʒi ə, -zi ə)

1. abnormal multiplication of cells.
2. enlargement of a part due to an abnormal numerical increase of its cells.
hy`per•plas′tic (-ˈplæs tɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.hyperplasia - abnormal increase in number of cells
dysplasia - abnormal development (of organs or cells) or an abnormal structure resulting from such growth
benign prostatic hyperplasia, BPH - enlarged prostate; appears to be part of the natural aging process


n. hiperplasia, proliferación excesiva de células normales en un tejido.


n hiperplasia; benign prostatic— hiperplasia prostática benigna; congenital adrenal — hiperplasia suprarrenal congénita
References in periodicals archive ?
The patented Spiral Luminal Flow[TM] technology was designed to prevent neointimal hyperplasia by decreasing turbulence and creating a spiral flow that mimics the blood flow of a native AV fistula into the venous system (Vascular Flow Technologies, 2017b).
Neointimal hyperplasia in coronary vein grafts: pathophysiology and prevention of a significant clinical problem.
The next steps in establishing the effect of the coating combinations on cell proliferation should include a revised method for viewing total number of cells within and determine optimal combinations to decrease cell proliferation and effectively neointimal hyperplasia once correlated in vivo.
Metallic Surface Treatment Using Electrochemical Polishing Decreases Thrombogenicity and Neointimal Hyperplasia of Coronary Stents.
Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia.
Ariste has completed pre-clinical models demonstrating proof-of-concept using ePTFE grafts coated with rapamycin and has achieved a significant reduction in neointimal hyperplasia, or scarring within the graft.
Conclusion: EPCs derived from human early fetal aorta were successfully transplanted into injured vessels and might inhibit neointimal hyperplasia after vascular injury.
Sirolimus acts by binding to FK506 binding protein-12 and inhibits restenosis cascade by blocking inflammation, neointimal hyperplasia, collagen synthesis and migration of smooth muscle cells (24).
The Combo Stent has demonstrated significantly lower neointimal hyperplasia, improved endothelial coverage relative to commercially available drug-eluting stents and lower presence of inflammation and foreign body reaction in multiple pre-clinical studies," said Renu Virmani, M.
Drug-eluting stents have been proposed as an alternative approach to decrease neointimal hyperplasia.