nerve growth factor

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nerve growth factor

n. Abbr. NGF
A protein that stimulates the growth of sympathetic and sensory nerve cells.

nerve growth factor

n
1. (Physiology) a polypeptide produced by neurones and their supporting tissues as well as some other tissues that stimulate the growth of neurones
2. (Physiology) any of various related polypeptides that promote the growth of neurones
Abbreviation: NGF

nerve′ growth` fac`tor



n.
a protein that promotes the growth, organization, and maintenance of sympathetic and some sensory nerve cells. Abbr.: NGF
[1965–70]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nerve growth factor - a protein that is involved in the growth of peripheral nerve cells
growth factor - a protein that is involved in cell differentiation and growth
References in periodicals archive ?
Previous studies have shown that nerve growth factors can promote the sprouting of proximal nerve stump to the distal stump by regulating the expression of Wnt5a in sympathetic neurons.
Lindsay, "Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons," The Journal of Neuroscience, vol.
Previous studies have suggested that EGCG protects nerve cells from oxidative-radical-stress-induced apoptosis [15], has anti-inflammatory and neuroprotective potential [16], modulates neurological function [17], activates nerve growth factors to induce neuritogenesis and reduce neuropathic pain after chronic constriction nerve injury [18], and stimulates regeneration of myelinated axons and minimizes histomorphological alterations caused by crush injury of the sciatic nerve [19].
Nerve growth factors or neurotrophins are proteins that enhance the growth potentialities of sensory and sympathetic nerve cells.
In recent years, these promising findings include a nasal spray that seems to stop cognitive decline, a vaccine that stimulates the immune system to attack toxic AD proteins, intravenous infusions of human gamma globulin proteins that have halted the progression of AD in a small number of patients, and genetic manipulation that boosts levels of nerve growth factors to restore healthy brain functioning.
Bradykinin and nerve growth factors play pivotal role in muscular mechanical hyperplasia after exercise (delayed-onset muscle soreness).
The team is investigating two new nerve growth factors. MANF (mesencephalic astrocyte-derived neurotrophic factor) and CDNF.
BLSI's products in development include: Altropane, a radio imaging agent for the diagnosis of PD and ADHD; Troponin I, a naturally-occurring anti-angiogenesis factor for the treatment of solid tumors; AF-1 and Inosine, nerve growth factors for the treatment of stroke, spinal cord and optic nerve injury; novel therapeutics for the treatment of PD and ADHD; and transcription factors that may control the expression of molecules associated with autoimmune disease and allergies.