(redirected from Neurodegenerative disease)
Also found in: Medical, Encyclopedia, Wikipedia.


 (no͝or′ō-dĭ-jĕn′ər-ə-tĭv, nyo͝or′-)
Of, relating to, or characterized by a progressive loss of neurons in the brain: neurodegenerative diseases.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
References in periodicals archive ?
(The Woodlands, TX) entered into a research agreement with The Methodist Hospital Research Institute to search for biomarkers and develop a suite of tests that directly impact the diagnosis of neurodegenerative diseases. Power3, in collaboration with Stan Appel, M.D., Chair of Neurology at the Methodist Neurological Institute, has completed clinical validation, testing serum proteins from over 600 patients, normal and neurodegenerative disease controls, including patients with Lou Gehrig's (ALS), Alzheimer's and Parkinson's diseases.
Washington, June 10 ( ANI ): The sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, scientists have claimed.
Approximately 5,600 people in the United States are diagnosed each year with ALS, a progressive neurodegenerative disease that is usually fatal within 2-5 years of diagnosis.
The collaboration is focused on using [F-18] MK-6240 as a biomarker in Ionis neurodegenerative disease research studies.
"iPierian's platform provides a unique approach to neurodegenerative disease drug development, incorporating human disease biology at the very beginning of the discovery process," said CEO Nancy Stagliano.
These nanoscale particles isolate extremely small quantities of protein clumps associated with the neurodegenerative disease.
According to the terms of the agreement, Forma will fund a multi-year research program at the University of Oxford focusing on DUBs implicated in the pathogenesis of neurodegenerative disease. DUBs are a family of over a hundred proteases that play important roles in protein and cellular homeostasis, processes that are critical to normal cell function.
Carver Associate Professor of Internal Medicine at the University of Iowa, the team is now employing a viral vector to introduce siRNAs into mouse models of human neurodegenerative disease.
EBG, and its partner, Cerveau Technologies, Inc., will work with their collective pharmaceutical industry partners to apply this technology in association with neurodegenerative disease modifying therapy development.
The EU Joint Programme on Neurodegenerative Disease Research (JPND)announced on Wednesday the establishment of a new cross-initiative action to link with the US National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to investigate common mechanisms and pathways in neurodegenerative diseases.
Under the terms of the agreement, FORMA will fund a multi- year research program at the University of Oxford focusing on DUBs implicated in the pathogenesis of neurodegenerative disease. We are excited about this collaboration with Oxford University that complements FORMA's innovative efforts in drug discovery and are confident that scientists at Oxford will help us rapidly advance these novel approaches to progressive neurological diseases, said Michael Ahlijanian, Head of Neurosciences at FORMA Therapeutics.