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Related to Neurofilaments: Neurofilament proteins


 (no͝or′ə-fĭl′ə-mənt, nyo͝or′-)
Any of the long, fine threads that make up a neurofibril.

neu′ro·fil′a·men′tous (-mĕn′təs) adj.
References in periodicals archive ?
In the sporadic form of ALS, neurodegeneration may result from protein aggregation, glutamate-mediated excitotoxicity, mitochondrial dysfunction, oxidative stress, deficiency in neurotrophic factors that leads to the intracellular accumulation of neurofilaments, and the interaction of multiple cell types (5).
It is believed that there are several factors that may contribute to the onset of the disease, such as excitotoxicity by neurotransmitter glutamate, accumulation of neurofilaments, deficiency Neurotrophic factors, immunity changes, physical trauma, persistent viral infections, as well as chemical and physical environmental factors.
7] Neurofilaments have been recognized in the pathogenesis of many diseases for, e.
Nitration of structural proteins, including neurofilaments and actin, can disrupt filament assembly with major pathological consequences [33].
Biomarkers of disease progression: cleaved amyloids, neurofilaments, orexin, prion protein, cleaved tau, and potential synapse markers.
These membranes do not contain neurofilaments and do not look like electron-dense extracellular matrix fibers such as collagen fibers.
Methylprednisolone also protects cell membrane proteins such as adenosine triphosphatase and neurofilaments that are responsible for the integrity of the cellular cytoskeleton.
Immunohistochemical studies were positive for chromogranin, synaptophysin and neurofilaments, but negative for desmin and CD99.
But with millions of cells, all carrying the human disease, to work with, Zhang's research group discovered the source of the tangles in the protein subunits that compose the neurofilaments.
7) Other substances detected immunohistochemically in the tumour include synaptophysin, chromogranin, neuron-specific enolase and neurofilaments.