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An ancient city of Bithynia in northwest Asia Minor. Dating from the fourth century bc, it flourished during Roman times. The Nicene Creed was adopted at an ecumenical council convened here by Constantine I in ad 325.
(Placename) a variant of Nicene
Ni•cene(naɪˈsin, ˈnaɪ sin)
of or pertaining to Nicaea.
[1350–1400; Middle English < Late Latin Nīcēnus, Nīcaenus]