Nitrosodiethylamine (NDEA) and nitrosodimethylamine (NDMA) have been suggested to represent the most potent nitroso compounds
. NDEA and NDMA have been exhibiting BML[D.sub.10] of 18 and 27 [micro]g/kg body weight/day, respectively :
9- Molybdenum has some effects on the synthesis of vitamin C in plants , which inhibit synthesis of nitroso compounds
in the human body .Mo has protective action against the induction of cancer in rats by organic N- nitroso compounds
when treated with sodium molybdate ( cited in ).
Plasma nitroso compounds
are decreased in patients with endothelial dysfunction.
Although the role of nitrates, nitrites and nitroso compounds
in the aetiology of colorectal cancer remains equivocal, a clear distinction between fresh and processed meats would be highly desirable for developing appropriate public health recommendations with respect to the role of meat in healthy diets, and (if necessary) for regulating the types and amounts of preservatives used in manufactured meat products.
Coverage encompasses all classes of nitric oxide donors, from organic nitrates to nitroso compounds
, guanidines, and metal-NO complexes.